公开(公告)号：US20240067758A1

公开(公告)日：2024-02-29

申请号：US18255213

申请日：2021-12-06

Applicant: UCB BIOPHARMA SRL

Inventor： Joseph Michael David RASTRICK ,  John Paul SILVA ,  Daniel John LIGHTWOOD ,  Ralph ADAMS ,  Roger Thomas PALFRAMAN ,  Kerry Louise TYSON ,  Peter Charles ELLIOTT ,  Seema MAYANK ,  Andrea Julie CROSBY ,  Emily Mary Cairistine BARRY ,  Seppe Frans Roman LEYSEN ,  Zainab AHDASH

IPC: C07K16/46 ,  C12N15/63 ,  A61P17/00

CPC classification number: C07K16/468 ,  C12N15/63 ,  A61P17/00 ,  C07K2317/31 ,  C07K2317/76 ,  C07K2317/565 ,  C07K2317/55 ,  C07K2317/622 ,  C07K2317/14

Abstract: The present invention relates to antibodies binding to IL13 and IL22. The invention provides novel multi-specific antibodies that bind to both IL13 and IL22 and compositions comprising an antibody that binds to IL13 and an antibody that binds to IL22. The invention further relates to therapeutic uses of the combination of anti-IL13 and anti-IL22 antibodies and multi-specific antibodies that bind to both IL13 and IL22.