公开(公告)号：US20250026856A1

公开(公告)日：2025-01-23

申请号：US18711331

申请日：2022-11-17

Applicant: UCB BIOPHARMA SRL

Inventor： Timothy Scott JOHNSON ,  John ATKINSON ,  Jorg Hans Wilhelm DISTLER ,  David John ABRAHAM

IPC: C07K16/40 ,  A61P17/00

Abstract: The present invention relates to an anti-transglutaminase type 2 (TG2) antibody for use in the treatment of a scleroderma disease, such as localized or systemic scleroderma.

公开(公告)号：US20250019463A1

公开(公告)日：2025-01-16

申请号：US18711286

申请日：2022-11-17

Applicant: UCB Biopharma SRL

Inventor： Timothy Scott JOHNSON ,  Ian Trollope JAMES ,  Patricia J. SIME ,  Thomas Henry THATCHER

IPC: C07K16/40 ,  A61K39/00 ,  A61P11/00

Abstract: The present invention relates to an anti-transglutaminase type 2 antibody that blocks transamidase activity of the enzyme for use in the treatment of progressive chronic interstitial lung disease, such as Idiopathic pulmonary fibrosis (IPF).