公开(公告)号：US20240140951A1

公开(公告)日：2024-05-02

申请号：US18267235

申请日：2021-12-06

Applicant: UCB Biopharma SRL

Inventor： Gareth Neil Brace ,  Shuyu Chu ,  Anne Marie Foley ,  James Andrew Johnson ,  Timothy John Norman ,  Joanna Rachel Quincey ,  James Thomas Reuberson ,  Robert Straker ,  Robert James Townsend

IPC: C07D487/04 ,  A61P29/00 ,  C07D519/00

CPC classification number: C07D487/04 ,  A61P29/00 ,  C07D519/00

Abstract: A series of substituted imidazo[1,2-b]pyridazine derivatives as defined herein, being potent modulators of human IL-17 activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including inflammatory and autoimmune disorders.