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公开(公告)号:US20160115466A1
公开(公告)日:2016-04-28
申请号:US14892881
申请日:2014-05-16
申请人: UCL BUSINESS PLC
发明人: Peter Taylor , David Negus
IPC分类号: C12N9/48 , A61K31/496 , C07K16/40 , A61K38/48
CPC分类号: C12N9/485 , A61K31/496 , A61K38/00 , A61K38/4813 , C07K16/40 , C12N9/18 , C12Y304/19
摘要: The present invention relates generally to methods and materials relating to newly characterised enzymes from Pusillimonas noertemannii, or variants thereof, capable degrading poly-γ-D-glutamic acid, for example as is present in the capsule of B. anthracis. Such depolymerases have utility as therapeutics.
摘要翻译: 本发明一般涉及与来自白喉属(Pusillimonas noertemannii)的新近表征的酶相关的方法和材料,或其变体,其能够降解聚-γ-D-谷氨酸,例如存在于炭疽杆菌胶囊中。 这种解聚酶具有治疗作用。