公开(公告)号：US20180311332A1

公开(公告)日：2018-11-01

申请号：US15771832

申请日：2016-10-28

申请人： UNIVERSIDAD COMPLUTENSE DE MADRID

发明人： Javier REGIDOR CERRILLO ,  David ARRANZ SOLÍS ,  Esther COLLANTES FERNÁNDEZ ,  Gema ÁLVAREZ GARCÍA ,  Luis Miguel ORTEGA MORA

IPC分类号： A61K39/012 ,  A61P33/02

CPC分类号： A61K39/002 ,  A61K2039/55577 ,  C07K14/44 ,  Y02A50/412

摘要： The present invention relates to new protein compositions, methods for producing said protein compositions, pharmaceutical compositions comprising said protein compositions and methods for treating infections caused by Neospora caninum. In particular, the present invention relates to a protein composition comprising the proteins specified in Table A in an amount of at least about 2 times (fold change) higher than the same protein present in the whole tachyzoite, as calculated by quantitative label-free liquid chromatography-tandem mass spectrometry (LC-MS/MS).