专利检索 ap:("UNIVERSIDAD DEL PAIS VASCO-EUSKAL HERRIKO UNIBERTSITATEA (UPV/EHU)") AND inv:"Alejandro Sänchez Barreiro" 第 1 页

1.

发明授权
Vehicles for the transfection of miRNAs 有权

公开(公告)号：US10888529B2

公开(公告)日：2021-01-12

申请号：US16091071

申请日：2017-04-04

申请人： UNIVERSIDAD DEL PAIS VASCO-EUSKAL HERRIKO UNIBERTSITATEA (UPV/EHU)

发明人： Alejandro Sänchez Barreiro , Inés Fernändez Piñeiro , Iker Badiola , Joana Märquez

IPC分类号： A61K9/51 , A61K31/7105 , B82B3/00 , A61K47/18 , B82Y5/00 , B82B1/00

摘要： The invention relates to a nanoparticle comprising: (i) between 60 wt.-% and 99 wt.-% sorbitan ester, relative to the total weight of the nanoparticle; (ii) a positively charged substance; and (iii) a miRNA. The invention also relates to the methods for producing same and to the uses thereof, particularly for therapeutic uses, such as cancer treatment.