公开(公告)号：US10689452B2

公开(公告)日：2020-06-23

申请号：US16091456

申请日：2017-04-04

Applicant: UNIVERSITÄT STUTTGART ,  BALIOPHARM AG

Inventor： Roland Kontermann ,  Klaus Pfizenmaier ,  Fabian Richter ,  Kirstin Zettlitz ,  Peter Scheurich ,  Andreas Herrmann

IPC: C07K16/28 ,  A61P37/06

Abstract: The invention provides for an inhibitor of the huTNFRI receptor which is a human or humanized antibody construct that monovalently recognizes huTNFRI through an antigen-binding moiety, which is characterized by specific CDR sequences, a pharmaceutical preparation thereof, method of producing the inhibitor and the medical use of the inhibitor.