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公开(公告)号：US10300048B2
公开(公告)日：2019-05-28
申请号：US15314105
申请日：2015-05-28
申请人： UNIVERSITAT BERN
IPC分类号： A61K31/426 , A61K31/427
摘要： The invention relates to a compound comprising the following general formula (1) for use in the treatment of psychiatric or neurological disorders and inflammation, in particular neuroinflammation: (1) wherein each of R1, R2 and R3 are selected independently from each other from alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl, aryl, heterocycle or heteroaryl.
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公开(公告)号：US10336792B2
公开(公告)日：2019-07-02
申请号：US15129846
申请日：2015-03-27
申请人： UNIVERSITAT BERN
发明人： Tamis Darbre , Jean-Louis Reymond , Michaela Stach
摘要： The invention relates to a peptide dendrimer described by a general formula X—(B2—[Y2]S-D1)2-B1—Z, wherein X is (D2)4 or (D3)8-(B3—[Y3]r-D2)4 or a higher analog, Y is a linkage moiety, Z is a central moiety; each B denotes a diaminoalkylcarboxylic acid moiety; each D is a hydrophobic or cationic amino acid, or a di- or tripeptide composed of hydrophobic and cationic amino acids, for use as a pharmaceutical.
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3.发明授权公开(公告)号：US10155754B2
公开(公告)日：2018-12-18
申请号：US15314067
申请日：2015-05-28
申请人： UNIVERSITAT BERN
IPC分类号： C07D277/20 , C07D417/06 , C07D277/54
摘要： The invention relates to a compound comprising the following general formula (1): and said compound for use as a medicament, in particular for use in the treatment psychiatric or neurological disorders and inflammation, in particular neuroinflammation: (formula 1) wherein each of R1, R2 and R3 are selected independently from each other from alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl, aryl, heterocycle, or heteroaryl.
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4.发明授权公开(公告)号：US10774077B2
公开(公告)日：2020-09-15
申请号：US16546328
申请日：2019-08-21
申请人： UNIVERSITAT BERN
IPC分类号： C07D277/20 , C07D417/06 , C07D277/54
摘要： The invention relates to a compound comprising the following general formula (1): and said compound for use as a medicament, in particular for use in the treatment psychiatric or neurological disorders and inflammation, in particular neuroinflammation: (formula 1) wherein each of R1, R2 and R3 are selected independently from each other from alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl, aryl, heterocycle, or heteroaryl.
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5.发明授权公开(公告)号：US10392377B2
公开(公告)日：2019-08-27
申请号：US16221634
申请日：2018-12-17
申请人： UNIVERSITAT BERN
IPC分类号： C07D277/20 , C07D417/06 , C07D277/54
摘要： The invention relates to a compound comprising the following general formula (1): and said compound for use as a medicament, in particular for use in the treatment psychiatric or neurological disorders and inflammation, in particular neuroinflammation: (formula 1) wherein each of R1, R2 and R3 are selected independently from each other from alkyl, alkoxy, alkenyl, alkynyl, cycloalkyl, aryl, heterocycle, or heteroaryl.
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