公开(公告)号：US11679098B2

公开(公告)日：2023-06-20

申请号：US16597027

申请日：2019-10-09

Applicant: UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.

Inventor： Paula J. Bates ,  Sarah A. Andres ,  Joseph A. Burlison ,  Levi Beverly ,  Nagaraju Miriyala

IPC: A61K31/045 ,  A61K31/4188 ,  A61K31/08 ,  A61K31/035 ,  A61K31/351 ,  A61K31/133 ,  A61K31/085 ,  A61K31/095 ,  A61K31/22 ,  A61K31/121

CPC classification number: A61K31/4188 ,  A61K31/035 ,  A61K31/045 ,  A61K31/08 ,  A61K31/085 ,  A61K31/095 ,  A61K31/121 ,  A61K31/133 ,  A61K31/22 ,  A61K31/351

Abstract: Some embodiments of the invention include methods of using a compound such as Formula (I), Formula (II), or I-1 (e.g., in compositions or in pharmaceutical compositions) for treating diseases (e.g., cancer such as chemo-resistant cancer or cancer-therapy-resistant cancer). Additional embodiments of the invention are also discussed herein.