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公开(公告)号：US10479785B2
公开(公告)日：2019-11-19
申请号：US15749652
申请日：2016-08-04
Applicant: UNIVERSITY OF SOUTH AUSTRALIA
Inventor： Shudong Wang , Solomon Tadesse Zeleke , Mingfeng Yu
IPC: C07D417/14 , A61P35/02
Abstract: A novel class of inhibitors of protein kinases that are useful in the treatment of cell proliferative diseases and conditions, and especially those characterised by over-expression of CDK4, CDK6 and/or cyclin D, including certain cancers of lung, breast, brain, central nervous system, colorectal cancer and leukaemias. The inhibitors have the general structure I:
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