公开(公告)号：US20230139938A1

公开(公告)日：2023-05-04

申请号：US17870593

申请日：2022-07-21

Applicant: UNIVERSITY OF SOUTH CAROLINA

Inventor： HIPPOKRATIS KIARIS ,  Ioulia Chatzistamou ,  Asieh Naderi ,  Bernardo Chavez

IPC: C07K16/24 ,  A61P11/00 ,  A61P29/00 ,  G01N33/50

Abstract: Methods for treating lung injury by administration of an anti-CCL8 antibody are disclosed. Also disclosed are methods for evaluating lung therapies by use of an animal model of the genus Peromyscus.

公开(公告)号：US20190359700A1

公开(公告)日：2019-11-28

申请号：US16371386

申请日：2019-04-01

Applicant: UNIVERSITY OF SOUTH CAROLINA

Inventor： HIPPOKRATIS KIARIS ,  Eleni Farmaki ,  Iolia Chatzistamolu ,  Vimala Kaza

IPC: C07K16/24 ,  C07K16/30 ,  A61K45/06 ,  A61K39/395 ,  C12Q1/686

Abstract: Anti-CCL8 antibodies and antigen binding fragments thereof are described. Antibodies and fragments thereof can be used for prevention of migration of breast cancer cells. Methods include delivery of an anti-CCL8 antibody or an antigen binding fragment thereof to an area including the breast cancer cells, e.g., delivery to a subject in need thereof in an effective amount.

公开(公告)号：US20200299374A1

公开(公告)日：2020-09-24

申请号：US16895407

申请日：2020-06-08

Applicant: UNIVERSITY OF SOUTH CAROLINA

Inventor： HIPPOKRATIS KIARIS ,  ELENI FARMAKI ,  IOULIA CHATZISTAMOU ,  VIMALA KAZA

IPC: C07K16/24 ,  C07K16/30 ,  A61K45/06 ,  C12Q1/686 ,  A61K39/395

Abstract: Anti-CCL8 antibodies and antigen binding fragments thereof are described. Antibodies and fragments thereof can be used for prevention of migration of breast cancer cells. Methods include delivery of an anti-CCL8 antibody or an antigen binding fragment thereof to an area including the breast cancer cells, e.g., delivery to a subject in need thereof in an effective amount.