公开(公告)号：US20170246237A1

公开(公告)日：2017-08-31

申请号：US15517839

申请日：2015-10-09

Applicant: UNIVERSITY OF STRATHCLYDE

Inventor： Rein ULIJN ,  Tell TUTTLE ,  Pim FREDERIX ,  Gary SCOTT ,  Yousef ABUL-HAIJA

IPC: A61K38/06 ,  C07K5/09 ,  B82Y40/00 ,  A61L15/60 ,  G06F19/16 ,  C07K5/087 ,  A61K9/00

CPC classification number: A61K38/06 ,  A61K9/0014 ,  A61L15/60 ,  B82Y40/00 ,  C07K5/0812 ,  C07K5/0815 ,  G16B15/00

Abstract: The present invention relates to a method of predicting the propensity of tripeptides to from aggregates in solution. The present invention also provides tripeptides which are able to form aggregates in solution, as well as uses thereof. The present invention also provides nanostructures formed by self-aggregation of tripeptides of the present invention. The present invention also provides pH responsive aggregates as well as methods of screening for the ability of a tripeptide to form a pH dependent aggregate or gel.