公开(公告)号：US20240148812A1

公开(公告)日：2024-05-09

申请号：US18386261

申请日：2023-11-02

申请人： USCAREPHARM CO.,LTD

发明人： Sukjin SONG ,  Juah SON ,  Mi-Ran CHA ,  Byulnim OH ,  Sangwoo BANG ,  Jinwook CHA

IPC分类号： A61K36/537 ,  A61K36/65 ,  A61P9/14

CPC分类号： A61K36/537 ,  A61K36/65 ,  A61P9/14 ,  A61K2236/33 ,  A61K2236/331 ,  A61K2236/333

摘要： The present disclosure relates to a pharmaceutical composition for preventing or treating diseases caused by vascular aging, including a Salvia miltiorrhiza extract or a Paeonia lactiflora extract as an active ingredient, wherein it was found that a single extract of each of Salvia miltiorrhiza and Paeonia lactiflora or a mixed extract of both mixed in a specific weight ratio showed effects of improving symptoms by vascular aging such as cytoprotection against cytotoxicity due to vascular aging, promotion of nitric oxide production, inhibition of collagen fiber production, suppression of vascular thickness increase, and inhibitory activities on fibrosis by collagen deposition, thereby being useful as a composition for preventing, treating, or ameliorating diseases or symptoms caused by vascular aging.

公开(公告)号：US20220257688A1

公开(公告)日：2022-08-18

申请号：US17628235

申请日：2020-08-12

申请人： USCAREPHARM CO.,LTD

发明人： Suk Jin SONG ,  Byulnim OH ,  Mi-Ran CHA ,  Sunhee KANG ,  Juah SON ,  Yunsung LEE

IPC分类号： A61K36/65 ,  A61K36/537 ,  A61P3/06

摘要： The present invention relates to a composition comprising a Salvia miltiorrhiza or Paeonia lactiflora extract as an active ingredient for prevention or treatment of lipid metabolism disorder and, more particularly, provides a pharmaceutical composition and a health functional food composition, each comprising a Salvia miltiorrhiza extract, a Paeonia lactiflora extract, or an extract from a mixture of Salvia miltiorrhiza and Paeonia lactiflora as an active ingredient for prevention or treatment of lipid metabolism disorder. The composition prevents the differentiation of preadipocyte cells to adipocyte cells, reduces blood triglyceride and cholesterol levels, and effectively suppresses fatty liver and visceral fat formation and as such, can be advantageously used as a pharmaceutical and food composition for prevention, alleviation, or treatment of lipid metabolism disorder.