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公开(公告)号:US20130123115A1
公开(公告)日:2013-05-16
申请号:US13578291
申请日:2011-02-11
申请人: Ulrich Kettling , Christoph Reisinger , Thomas Brück , Andre Koltermann , Jochen Gerlach , Isabel Unterstrasser , Lutz Röcher , Markus Rarbach , Jörg Claren , Andreas Kohl , Jan Carsten Pieck , Dominik Schlosser
发明人: Ulrich Kettling , Christoph Reisinger , Thomas Brück , Andre Koltermann , Jochen Gerlach , Isabel Unterstrasser , Lutz Röcher , Markus Rarbach , Jörg Claren , Andreas Kohl , Jan Carsten Pieck , Dominik Schlosser
IPC分类号: C12N9/42
CPC分类号: C12N9/2437 , C12N9/24 , C12Y302/01091
摘要: The invention discloses cellulase enzymes with optimized properties for processing of cellulose- and lignocellulose-containing substrates. In particular, cellobiohydrolase enzymes with preferred characteristics are disclosed. The present invention provides fusion, insertion, deletion and/or substitution variants of such enzymes. Enzyme variants have enhanced thermostability, proteolytic stability, specific activity and/or stability at extreme pH. Nucleic acid molecules encoding said enzymes, a composition comprising said enzymes, a method for preparation, and the use for cellulose processing and/or for the production of biofuels are disclosed.
摘要翻译: 本发明公开了具有优化的用于加工含纤维素和木质素纤维素的底物的纤维素酶。 特别地,公开了具有优选特性的纤维二糖水解酶。 本发明提供了这种酶的融合,插入,缺失和/或取代变体。 酶变体在极端pH下具有增强的热稳定性,蛋白水解稳定性,比活度和/或稳定性。 公开了编码所述酶的核酸分子,包含所述酶的组合物,制备方法以及用于纤维素加工和/或生产生物燃料的用途。
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公开(公告)号:US09458443B2
公开(公告)日:2016-10-04
申请号:US13578291
申请日:2011-02-11
申请人: Ulrich Kettling , Christoph Reisinger , Thomas Brück , Andre Koltermann , Jochen Gerlach , Isabel Unterstrasser , Lutz Röcher , Markus Rarbach , Jörg Claren , Andreas Kohl , Jan Carsten Pieck , Dominik Schlosser
发明人: Ulrich Kettling , Christoph Reisinger , Thomas Brück , Andre Koltermann , Jochen Gerlach , Isabel Unterstrasser , Lutz Röcher , Markus Rarbach , Jörg Claren , Andreas Kohl , Jan Carsten Pieck , Dominik Schlosser
IPC分类号: C12N9/42
CPC分类号: C12N9/2437 , C12N9/24 , C12Y302/01091
摘要: The invention discloses cellulase enzymes with optimized properties for processing of cellulose- and lignocellulose-containing substrates. In particular, cellobiohydrolase enzymes with preferred characteristics are disclosed. The present invention provides fusion, insertion, deletion and/or substitution variants of such enzymes. Enzyme variants have enhanced thermostability, proteolytic stability, specific activity and/or stability at extreme pH. Nucleic acid molecules encoding said enzymes, a composition comprising said enzymes, a method for preparation, and the use for cellulose processing and/or for the production of biofuels are disclosed.
摘要翻译: 本发明公开了具有优化的用于加工含纤维素和木质素纤维素的底物的纤维素酶。 特别地,公开了具有优选特性的纤维二糖水解酶。 本发明提供了这种酶的融合,插入,缺失和/或取代变体。 酶变体在极端pH下具有增强的热稳定性,蛋白水解稳定性,比活性和/或稳定性。 公开了编码所述酶的核酸分子,包含所述酶的组合物,制备方法以及用于纤维素加工和/或生产生物燃料的用途。
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