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公开(公告)号:US20070265194A1
公开(公告)日:2007-11-15
申请号:US11732797
申请日:2007-04-04
申请人: Ulrich Schubert , Hans Will , Uwe Tessmer , Husseyin Sirma , Alexij Prassolow , Evelyn Schubert , Heinz Hohenberg , Reinhold Welker
发明人: Ulrich Schubert , Hans Will , Uwe Tessmer , Husseyin Sirma , Alexij Prassolow , Evelyn Schubert , Heinz Hohenberg , Reinhold Welker
IPC分类号: A61K38/00 , A61K31/21 , A61K31/4015 , A61K47/00 , A61P31/18 , A61P31/12 , A61K31/585 , A61K31/69
CPC分类号: A61K31/5375 , A61K31/00 , A61K31/166 , A61K31/336 , A61K31/365 , A61K31/4015 , A61K31/407 , A61K31/415 , A61K31/47 , A61K31/704 , A61K38/06 , A61K38/07 , A61K38/55
摘要: The invention relates to methods of treating a hepatitus virus infection by administering a therapeutically effective amount of a proteasome inhibitor and a pharmaceutically acceptable carrier to a subject in need thereof. Preferably, the protesome in hibitor inhibits or regulates a ubiquitin proteasome pathway.
摘要翻译: 本发明涉及通过向有需要的受试者施用治疗有效量的蛋白酶体抑制剂和药学上可接受的载体来治疗肝炎病毒感染的方法。 优选地,hibitor中的protesome抑制或调节泛素蛋白酶体途径。