公开(公告)号：US20240249797A1

公开(公告)日：2024-07-25

申请号：US18424587

申请日：2024-01-26

Applicant: Ultima Genomics, Inc.

Inventor： Yoav ETZIONI ,  Edward PERELMAN ,  Asaf HALLE

IPC: G16B30/00 ,  C12Q1/6874 ,  G16B40/20

CPC classification number: G16B30/00 ,  C12Q1/6874 ,  G16B40/20

Abstract: Methods for updating a system comprising a sequencer are described herein. In some exemplary methods, the system is updated through generating sequencing data for a plurality of nucleic acid molecule colonies, selecting sequencing data for a subset of the nucleic acid molecule colonies, calling preliminary sequences for the subset of the nucleic acid colonies, mapping the called preliminary sequences to a known reference sequence, and updating the pre-trained sequencer-specific machine-learning model. Also described herein are systems for carrying out such methods and computer readable memory for storing such methods.

公开(公告)号：US20230343416A1

公开(公告)日：2023-10-26

申请号：US18025603

申请日：2021-09-10

Applicant: Ultima Genomics, Inc.

Inventor： Yoav ETZIONI ,  Omer BARAD ,  Avishai BARTOV ,  Ilya SOIFER ,  Ehud AMITAI ,  Asaf HALLE

IPC: G16B40/10 ,  C12Q1/6869 ,  G16B40/20 ,  G16B30/10 ,  G06N3/0464

CPC classification number: G16B40/10 ,  C12Q1/6869 ,  G16B40/20 ,  G16B30/10 ,  G06N3/0464

Abstract: The present disclosure provides methods, systems, and media for accurate and efficient estimation of a genome of a genus. The methods and systems described herein may be used to accurately determine a base sequence of a polynucleotide. Additionally, the methods and systems may be used to identify base variants of a polynucleotide.