公开(公告)号：US20220082578A1

公开(公告)日：2022-03-17

申请号：US17402508

申请日：2021-08-14

Applicant: Universitätsspital Basel

Inventor： Matthias E LIECHTI ,  Karolina Elzbieta KOLACZYNSKA ,  Urs Philipp DUTHALER

IPC: G01N33/94

Abstract: A method of measuring and identifying metabolites of a tryptamine compound, by obtaining a sample from an individual, and measuring and identifying metabolites of the tryptamine compound in the sample by performing a LC-MS/MS analysis. A method of adjusting dosing in patients with tryptamine compound-assisted psychotherapy in therapeutic drug monitoring (TDM), by obtaining a sample from an individual, measuring and identifying metabolites of the tryptamine compounds in the sample by performing a LC-MS/MS analysis, and adjusting a dose of the tryptamine compounds based on the measured metabolites.