公开(公告)号：US20180077937A1

公开(公告)日：2018-03-22

申请号：US15708080

申请日：2017-09-18

申请人： University Court of The University of St Andrews

发明人： Russell Edward Morris ,  Paul Stewart Wheatley ,  Stewart Warrender ,  Morven Duncan

IPC分类号： A01N55/02 ,  C07F15/04 ,  C07F3/06 ,  C07F1/10 ,  C07F1/00 ,  A01N25/34 ,  C07C51/41 ,  C07C65/05 ,  A01N59/16 ,  A01N37/40

CPC分类号： A01N55/02 ,  A01N25/34 ,  A01N37/40 ,  A01N59/16 ,  A01N2300/00 ,  C07C51/418 ,  C07C65/05 ,  C07F1/005 ,  C07F1/10 ,  C07F3/06 ,  C07F15/045 ,  A01N37/10

摘要： The present invention relates to the synthesis of a variety of metal organic frameworks (MOFs) using low temperature and solvents which are considered to be not particularly harmful to the environment. There is also provided novel MOFs which may be made by the desired processes.

公开(公告)号：US20200147127A1

公开(公告)日：2020-05-14

申请号：US16568560

申请日：2019-09-12

申请人： University Court of the University of St. Andrews

发明人： Morven Duncan ,  Stewart Warrender ,  Russell Edward Morris ,  Damiano Cattaneo

IPC分类号： A61K33/00 ,  B01J20/28 ,  A61K31/496 ,  A61K31/155 ,  A61K9/14 ,  A61K8/19 ,  A61K47/52 ,  B01J20/22

摘要： Disclosed are metal organic framework materials (MOFs), comprising an extra-framework NO releasing compound within the internal pores and/or channels of the MOF, the NO-releasing compounds and their preparation and uses. The MOFs and NO-releasing compounds are capable of releasing NO on application of an external stimulus and may provide materials with multiple modes of antibacterial and/or drug action.

公开(公告)号：US11344571B2

公开(公告)日：2022-05-31

申请号：US16568560

申请日：2019-09-12

申请人： University Court of the University of St. Andrews

发明人： Morven Duncan ,  Stewart Warrender ,  Russell Edward Morris ,  Damiano Cattaneo

IPC分类号： A61K33/00 ,  A61K8/19 ,  A61K9/14 ,  A61K31/155 ,  A61K31/496 ,  A61K47/52 ,  B01J20/22 ,  B01J20/28

摘要： Disclosed are metal organic framework materials (MOFs), comprising an extra-framework NO releasing compound within the internal pores and/or channels of the MOF, the NO-releasing compounds and their preparation and uses. The MOFs and NO-releasing compounds are capable of releasing NO on application of an external stimulus and may provide materials with multiple modes of antibacterial and/or drug action.

公开(公告)号：US20180264033A1

公开(公告)日：2018-09-20

申请号：US15547670

申请日：2016-01-28

申请人： University Court of the University of St. Andrews

发明人： Morven Duncan ,  Stewart Warrender ,  Russell Edward Morris ,  Damiano Cattaneo

IPC分类号： A61K33/00 ,  A61K31/155 ,  A61K31/496 ,  A61K47/52 ,  A61K9/14 ,  B01J20/22 ,  B01J20/28 ,  A61K8/19

摘要： Disclosed are metal organic framework materials (MOFs), comprising an extra-framework NO releasing compound within the internal pores and/or channels of the MOF, the NO-releasing compounds and their preparation and uses. The MOFs and NO-releasing compounds are capable of releasing NO on application of an external stimulus and may provide materials with multiple modes of antibacterial and/or drug action.

公开(公告)号：US09763452B2

公开(公告)日：2017-09-19

申请号：US14406746

申请日：2013-06-10

申请人： University Court of The University of St Andrews

发明人： Russell Edward Morris ,  Paul Stewart Wheatley ,  Stewart Warrender ,  Morven Duncan

IPC分类号： C07C65/05 ,  A01N55/02 ,  C07F15/04 ,  C07F1/10 ,  C07F3/06 ,  A01N59/16 ,  C07F1/00 ,  C07C51/41

CPC分类号： A01N55/02 ,  A01N25/34 ,  A01N37/40 ,  A01N59/16 ,  A01N2300/00 ,  C07C51/418 ,  C07C65/05 ,  C07F1/005 ,  C07F1/10 ,  C07F3/06 ,  C07F15/045 ,  A01N37/10

摘要： The present invention relates to the synthesis of a variety of metal organic frameworks (MOFs) using low temperature and solvents which are considered to be not particularly harmful to the environment. There is also provided novel MOFs which may be made by the desired processes.

公开(公告)号：US10449215B2

公开(公告)日：2019-10-22

申请号：US15547670

申请日：2016-01-28

申请人： University Court of the University of St. Andrews

发明人： Morven Duncan ,  Stewart Warrender ,  Russell Edward Morris ,  Damiano Cattaneo

IPC分类号： A61K33/00 ,  A61K31/155 ,  A61K47/52 ,  A61K8/19 ,  A61K9/14 ,  A61K31/496 ,  B01J20/28 ,  B01J20/22

摘要： Disclosed are metal organic framework materials (MOFs), comprising an extra-framework NO releasing compound within the internal pores and/or channels of the MOF, the NO-releasing compounds and their preparation and uses. The MOFs and NO-releasing compounds are capable of releasing NO on application of an external stimulus and may provide materials with multiple modes of antibacterial and/or drug action.

公开(公告)号：US10357037B2

公开(公告)日：2019-07-23

申请号：US15708080

申请日：2017-09-18

申请人： University Court of The University of St Andrews

发明人： Russell Edward Morris ,  Paul Stewart Wheatley ,  Stewart Warrender ,  Morven Duncan

IPC分类号： A01N55/02 ,  C07F15/04 ,  C07F1/10 ,  C07F3/06 ,  A01N59/16 ,  C07F1/00 ,  C07C51/41 ,  A01N25/34 ,  A01N37/40 ,  C07C65/05

摘要： The present invention relates to the synthesis of a variety of metal organic frameworks (MOFs) using low temperature and solvents which are considered to be not particularly harmful to the environment. There is also provided novel MOFs which may be made by the desired processes.

公开(公告)号：US20150173368A1

公开(公告)日：2015-06-25

申请号：US14406746

申请日：2013-06-10

申请人： UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS

发明人： Russell Edward Morris ,  Paul Stewart Wheatley ,  Stewart Warrender ,  Morven Duncan

IPC分类号： A01N55/02 ,  C07F15/04 ,  C07F1/00 ,  C07F3/06

CPC分类号： A01N55/02 ,  A01N25/34 ,  A01N37/40 ,  A01N59/16 ,  A01N2300/00 ,  C07C51/418 ,  C07C65/05 ,  C07F1/005 ,  C07F1/10 ,  C07F3/06 ,  C07F15/045 ,  A01N37/10

摘要： The present invention relates to the synthesis of a variety of metal organic frameworks (MOFs) using low temperature and solvents which are considered to be not particularly harmful to the environment. There is also provided novel MOFs which may be made by the desired processes.

摘要翻译： 本发明涉及使用被认为对环境没有特别有害的低温和溶剂的各种金属有机骨架（MOF）的合成。 还提供了可以通过所需方法制备的新型MOF。