公开(公告)号：US09636327B2

公开(公告)日：2017-05-02

申请号：US14889767

申请日：2014-05-05

申请人： University Health Network, Toronto General Hospital

发明人： Kumaraswamy Nanthakumar

IPC分类号： A61K31/41 ,  A61K31/415 ,  A61K31/4178 ,  A61K45/06 ,  A61K31/422

CPC分类号： A61K31/4178 ,  A61K31/422 ,  A61K45/06 ,  A61K2300/00

摘要： The present description relates to methods of administering effective amounts of an anti-arrhythmic agent, e.g., dantrolene, azumolene or a pharmaceutically acceptable salt thereof, for the acute treatment of cardiac arrhythmias, e.g., atrial fibrillation, premature ventricular contraction, ventricular tachycardia or ventricular fibrillation, and prevention of subsequent cardiac arrhythmias, wherein the methods effectuate a reduction in morbidity and mortality.

公开(公告)号：US20160101085A1

公开(公告)日：2016-04-14

申请号：US14889767

申请日：2014-05-05

申请人： University Health Network, Toronto General Hospital

发明人： Kumaraswamy Nanthakumar

IPC分类号： A61K31/4178 ,  A61K31/422 ,  A61K45/06

CPC分类号： A61K31/4178 ,  A61K31/422 ,  A61K45/06 ,  A61K2300/00

摘要： The present description relates to methods of administering effective amounts of an anti-arrhythmic agent, e.g., dantrolene, azumolene or a pharmaceutically acceptable salt thereof, for the acute treatment of cardiac arrhythmias, e.g., atrial fibrillation, premature ventricular contraction, ventricular tachycardia or ventricular fibrillation, and prevention of subsequent cardiac arrhythmias, wherein the methods effectuate a reduction in morbidity and mortality.

摘要翻译： 本说明书涉及施用有效量的抗心律失常药物（例如丹曲林，azumolene或其药学上可接受的盐）用于急性治疗心律失常的方法，例如心房颤动，室性早搏，室性心动过速或室性心律失常 原纤维化和预防随后的心律失常，其中所述方法降低发病率和死亡率。