公开(公告)号：US10750746B2

公开(公告)日：2020-08-25

申请号：US16192248

申请日：2018-11-15

Applicant: University of Florida Research Foundation, Inc. ,  STC.UNM

Inventor： David G. Whitten ,  Kirk S. Schanze ,  Anand Parthasarathy ,  Eunkyung Ji ,  Motokatsu Ogawa ,  Thomas S. Corbitt ,  Dimitri Dascier ,  Ying Wang ,  Linnea K. Ista ,  Eric H. Hill

IPC: A01N43/90 ,  C07C217/14 ,  C07C309/11 ,  A01N25/10 ,  C07D409/14 ,  C07C217/20 ,  C07C309/24 ,  C07D333/16 ,  C07D487/08 ,  C08G61/02 ,  C08G75/00 ,  C08G61/12 ,  A01N25/08 ,  A01N33/10 ,  A01N33/12 ,  A01N41/04 ,  A01N43/10

Abstract: The present disclosure provides novel poly(phenylene ethynylene) (PPE) compounds, methods for synthesizing these compounds, and materials and substances incorporating these compounds. The various PPEs show antibacterial, antiviral and antifungal activity.

公开(公告)号：US10174042B2

公开(公告)日：2019-01-08

申请号：US15348756

申请日：2016-11-10

Applicant: University of Florida Research Foundation, Inc. ,  STC.UNM

Inventor： David G. Whitten ,  Kirk S. Schanze ,  Anand Parthasarathy ,  Eunkyung Ji ,  Motokatsu Ogawa ,  Thomas S. Corbitt ,  Dimitri Dascier ,  Ying Wang ,  Linnea K. Ista ,  Eric H. Hill

IPC: C07D487/08 ,  C07C217/14 ,  C07C309/11 ,  C07C217/20 ,  C07C309/24 ,  C07D333/16 ,  C08G61/02 ,  C08G75/00 ,  C08G61/12

Abstract: The present disclosure provides novel poly(phenylene ethynylene) (PPE) compounds, methods for synthesizing these compounds, and materials and substances incorporating these compounds. The various PPEs show antibacterial, antiviral and antifungal activity.

公开(公告)号：US20190116797A1

公开(公告)日：2019-04-25

申请号：US16192248

申请日：2018-11-15

Applicant: University of Florida Research Foundation, Inc. ,  STC.UNM

Inventor： David G. Whitten ,  Kirk S. Schanze ,  Anand Parthasarathy ,  Eunkyung Ji ,  Motokatsu Ogawa ,  Thomas S. Corbitt ,  Dimitri Dascier ,  Ying Wang ,  Linnea K. Ista ,  Eric H. Hill

IPC: A01N43/90 ,  C08G61/02 ,  C07D409/14 ,  C08G75/00 ,  A01N25/08 ,  A01N33/10 ,  C07C217/14 ,  A01N25/10 ,  A01N33/12 ,  A01N41/04 ,  A01N43/10 ,  C08G61/12 ,  C07D487/08 ,  C07D333/16 ,  C07C309/24 ,  C07C217/20 ,  C07C309/11

Abstract: The present disclosure provides novel poly(phenylene ethynylene) (PPE) compounds, methods for synthesizing these compounds, and materials and substances incorporating these compounds. The various PPEs show antibacterial, antiviral and antifungal activity.

公开(公告)号：US10058099B2

公开(公告)日：2018-08-28

申请号：US15368148

申请日：2016-12-02

Applicant: University of Florida Research Foundation, Inc. ,  STC.UNM

Inventor： David G. Whitten ,  Kirk S. Schanze ,  Eunkyung Ji ,  Dimitri Dascier ,  Anand Parthasarathy ,  Thomas S. Corbitt ,  Kirsten Cicotte ,  Elizabeth LeBleu Dirk ,  Xuzhi Zhu

IPC: A01N43/90 ,  A61L15/46 ,  A01N33/12 ,  A01N43/10 ,  A01N25/34 ,  A01N37/10 ,  A61L15/20 ,  D01H7/00

CPC classification number: A01N43/90 ,  A01N25/34 ,  A01N33/12 ,  A01N37/10 ,  A01N43/10 ,  A61L15/20 ,  A61L15/46 ,  A61L2300/208 ,  A61L2300/404 ,  D01H7/00 ,  A01N59/00 ,  A01N2300/00

Abstract: The invention provides methods and materials for decontamination of surfaces and fabrics, such as non-woven fabrics, that are contaminated with infestations of microorganisms such as bacteria. Biocidal oligomers having conjugated oligo-(aryl/heteroaryl ethynyl) structures and comprising at least one cationic group can be used to decontaminate infested surfaces in the presence of oxygen and, optionally, illumination. Fibers incorporating biocidal oligomers having conjugated oligo-(aryl/heteroaryl ethynyl) structures and comprising at least one cationic group, wherein the oligomer is physically associated with or covalently bonded to, or both, the fiber-forming polymer can be used to form non-woven mats. Biocidal non-woven mats prepared by methods of the invention, incorporating the biocidal oligomers, can be used to suppress bacterial growth in wound and surgical dressings and personal hygiene products.

公开(公告)号：US20170164614A1

公开(公告)日：2017-06-15

申请号：US15368148

申请日：2016-12-02

Applicant: University of Florida Research Foundation, Inc. ,  STC.UNM

Inventor： David G. Whitten ,  Kirk S. Schanze ,  Eunkyung Ji ,  Dimitri Dascier ,  Anand Parthasarathy ,  Thomas S. Corbitt ,  Kirsten Cicotte ,  Elizabeth LeBleu Dirk ,  Xuzhi Zhu

IPC: A01N43/90 ,  A01N25/34 ,  D01H7/00 ,  A01N33/12 ,  A01N43/10 ,  A61L15/46 ,  A61L15/20

CPC classification number: A01N43/90 ,  A01N25/34 ,  A01N33/12 ,  A01N37/10 ,  A01N43/10 ,  A61L15/20 ,  A61L15/46 ,  A61L2300/208 ,  A61L2300/404 ,  D01H7/00 ,  A01N59/00 ,  A01N2300/00

Abstract: The invention provides methods and materials for decontamination of surfaces and fabrics, such as non-woven fabrics, that are contaminated with infestations of microorganisms such as bacteria. Biocidal oligomers having conjugated oligo-(aryl/heteroaryl ethynyl) structures and comprising at least one cationic group can be used to decontaminate infested surfaces in the presence of oxygen and, optionally, illumination. Fibers incorporating biocidal oligomers having conjugated oligo-(aryl/heteroaryl ethynyl) structures and comprising at least one cationic group, wherein the oligomer is physically associated with or covalently bonded to, or both, the fiber-forming polymer can be used to form non-woven mats. Biocidal non-woven mats prepared by methods of the invention, incorporating the biocidal oligomers, can be used to suppress bacterial growth in wound and surgical dressings and personal hygiene products.