公开(公告)号：US11731934B2

公开(公告)日：2023-08-22

申请号：US17000180

申请日：2020-08-21

申请人： University of Florida Research Foundation, Inc. ,  The Scripps Research Institute

发明人： Daiqing Liao ,  William R. Roush ,  Ryan L. Stowe

IPC分类号： C07C233/77 ,  A61K31/166 ,  C07C243/38 ,  A61K45/06 ,  C07C247/12 ,  C07D239/26 ,  C07D213/86 ,  A61K31/4406 ,  A61K31/505 ,  C07C233/78 ,  C07D213/44 ,  C07D239/48

CPC分类号： C07C233/77 ,  A61K31/166 ,  A61K31/4406 ,  A61K31/505 ,  A61K45/06 ,  C07C233/78 ,  C07C243/38 ,  C07C247/12 ,  C07D213/44 ,  C07D213/86 ,  C07D239/26 ,  C07D239/48 ,  C07C2601/08 ,  A61K31/166 ,  A61K2300/00

摘要： The instant invention describes hydrazide-containing compounds having therapeutic activity, and methods of treating disorders such as cancer, tumors and cell proliferation related disorders, or affect cell differentiation, dedifferentiation or transdifferentiation.

公开(公告)号：US10807944B2

公开(公告)日：2020-10-20

申请号：US15301508

申请日：2015-03-30

申请人： University of Florida Research Foundation, Inc. ,  The Scripps Research Institute

发明人： Daiqing Liao ,  William R. Roush ,  Ryan L. Stowe

IPC分类号： C07C233/77 ,  A61K31/166 ,  C07C243/38 ,  A61K45/06 ,  C07C247/12 ,  C07D239/26 ,  C07D213/86 ,  A61K31/4406 ,  A61K31/505 ,  C07C233/78 ,  C07D213/44 ,  C07D239/48

摘要： The instant invention describes hydrazide-containing compounds having therapeutic activity, and methods of treating disorders such as cancer, tumors and cell proliferation related disorders, or affect cell differentiation, dedifferentiation or transdifferentiation.