公开(公告)号：US20240269239A1

公开(公告)日：2024-08-15

申请号：US18274166

申请日：2022-01-27

Applicant: University of Kansas

Inventor： Kyle APLEY ,  Mark FARRELL ,  Cory BERKLAND

IPC: A61K38/28 ,  A61K38/48 ,  A61K47/54 ,  A61K47/60 ,  A61P3/10

CPC classification number: A61K38/28 ,  A61K38/48 ,  A61K39/0008 ,  A61K47/545 ,  A61K47/549 ,  A61K47/60 ,  A61P3/10 ,  C07D249/04 ,  C07H15/26 ,  C07K14/62

Abstract: The present disclosure provides conjugates, methods of making the same, and uses thereof. The conjugates of the present technology are useful in inducing anergy in insulin-binding B cells.