公开(公告)号：US20230181769A1

公开(公告)日：2023-06-15

申请号：US17641787

申请日：2020-09-10

Applicant: University of Louisville Research Foundation, Inc.

Inventor： Nicholas C. Allen ,  Paula J. Bates ,  Martin G. O'Toole

IPC: A61K49/18 ,  A61K47/69 ,  A61K47/60 ,  A61P35/00

CPC classification number: A61K49/186 ,  A61K47/6929 ,  A61K47/60 ,  A61P35/00

Abstract: A composition comprises an anti-nucleolin agent and PEG conjugated to nanoparticles. Preferably the nanoparticles have an average diameter of 1 to 50 nm. Preferably, the nanopanicles comprise at least one inorganic material selected from the group consisting of metals, elements and oxides.