公开(公告)号：US20230332180A1

公开(公告)日：2023-10-19

申请号：US18297808

申请日：2023-04-10

Applicant: University of Massachusetts

Inventor： Guangping Gao ,  Phillip Tai ,  Manish Muhuri ,  Wei Zhan

IPC: C12N15/86 ,  C12N15/113 ,  A61K31/7088

CPC classification number: C12N15/86 ,  C12N15/113 ,  A61K31/7088 ,  C12N2330/51 ,  C12N2750/14143 ,  C12N2310/141 ,  C12N2320/32 ,  C12N2750/14171

Abstract: The disclosure, in some aspects, relates to nucleic acids, compositions and kits useful for gene therapy with reduced immune response to transgene products.

公开(公告)号：US11655483B2

公开(公告)日：2023-05-23

申请号：US17581306

申请日：2022-01-21

Applicant: University of Massachusetts

Inventor： Guangping Gao ,  Phillip Tai ,  Manish Muhuri ,  Wei Zhan

IPC: C12N15/86 ,  A61K31/7088 ,  C12N15/113

CPC classification number: C12N15/86 ,  A61K31/7088 ,  C12N15/113 ,  C12N2310/141 ,  C12N2320/32 ,  C12N2330/51 ,  C12N2750/14143 ,  C12N2750/14171

Abstract: The disclosure, in some aspects, relates to nucleic acids, compositions and kits useful for gene therapy with reduced immune response to transgene products.

公开(公告)号：US20220235372A1

公开(公告)日：2022-07-28

申请号：US17581306

申请日：2022-01-21

Applicant: University of Massachusetts

Inventor： Guangping Gao ,  Phillip Tai ,  Manish Muhuri ,  Wei Zhan

IPC: C12N15/86 ,  C12N15/113 ,  A61K31/7088

Abstract: The disclosure, in some aspects, relates to nucleic acids, compositions and kits useful for gene therapy with reduced immune response to transgene products.