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公开(公告)号：US20220323648A1
公开(公告)日：2022-10-13
申请号：US17762858
申请日：2020-09-30
发明人： Lorenzo Soletti , Bryan Brown , Josh Bowman , Nicole Cwalina , Brandon Burger , J. Christopher Flaherty
IPC分类号： A61L27/36
摘要： Systems, devices, and methods for treating a nerve injury in a patient are provided herein. The system includes an extracellular matrix, a neutralizing element, and a reconstituting element. The extracellular matrix is configured to promote and/or sustain the growth of tissue and/or associated tissue properties proximate the nerve injury.
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公开(公告)号：US20170340432A1
公开(公告)日：2017-11-30
申请号：US15453115
申请日：2017-03-08
发明人： Mohammed S. El-Kurdi , J. Christopher Flaherty , Yi Hong , Jonathan McGrath , Lorenzo Soletti , John J. Stankus , David A. Vorp , William R. Wagner
CPC分类号： A61F2/06 , A61F2/04 , A61F2/062 , A61F2002/072
摘要： A tubular tissue graft device is provided comprising a tubular member and a restrictive fiber matrix of a bioerodible polymer about a circumference of the tubular tissue. The matrix may be electrospun onto the tubular tissue. In one embodiment, the tubular tissue is from a vein, such as a saphenous vein, useful as an arterial graft, for example and without limitation, in a coronary artery bypass procedure. Also provided is method of preparing a tubular graft comprising depositing a fiber matrix of a bioerodible polymer about a perimeter of a tubular tissue to produce a tubular tissue graft device. A cardiac bypass method comprising bypassing a coronary artery with a tubular tissue graft device comprising a vein and a restrictive fiber matrix of a bioerodible polymer about a circumference of the vein also is provided.
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公开(公告)号：US20200237494A1
公开(公告)日：2020-07-30
申请号：US16577579
申请日：2019-09-20
发明人： Mohammed S. El-Kurdi , William R. Wagner , David A. Vorp , John J. Stankus , Lorenzo Soletti , Jonathan McGrath , Yi Hong , J. Christopher Flaherty
IPC分类号： A61F2/06
摘要： A tubular tissue graft device is provided comprising a tubular member and a restrictive fiber matrix of a bioerodible polymer about a circumference of the tubular tissue. The matrix may be electrospun onto the tubular tissue. In one embodiment, the tubular tissue is from a vein, such as a saphenous vein, useful as an arterial graft, for example and without limitation, in a coronary artery bypass procedure. Also provided is method of preparing a tubular graft comprising depositing a fiber matrix of a bioerodible polymer about a perimeter of a tubular tissue to produce a tubular tissue graft device. A cardiac bypass method comprising bypassing a coronary artery with a tubular tissue graft device comprising a vein and a restrictive fiber matrix of a bioerodible polymer about a circumference of the vein also is provided.
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公开(公告)号：US20240299155A1
公开(公告)日：2024-09-12
申请号：US18505610
申请日：2023-11-09
发明人： Mohammed S. El-Kurdi , William R. Wagner , David A. Vorp , John J. Stankus , Lorenzo Soletti , Jonathan McGrath , Yi Hong , J. Christopher Flaherty
CPC分类号： A61F2/06 , A61F2/04 , A61F2/062 , A61F2002/072
摘要： A tubular tissue graft device is provided comprising a tubular member and a restrictive fiber matrix of a bioerodible polymer about a circumference of the tubular tissue. The matrix may be electrospun onto the tubular tissue. In one embodiment, the tubular tissue is from a vein, such as a saphenous vein, useful as an arterial graft, for example and without limitation, in a coronary artery bypass procedure. Also provided is method of preparing a tubular graft comprising depositing a fiber matrix of a bioerodible polymer about a perimeter of a tubular tissue to produce a tubular tissue graft device. A cardiac bypass method comprising bypassing a coronary artery with a tubular tissue graft device comprising a vein and a restrictive fiber matrix of a bioerodible polymer about a circumference of the vein also is provided.
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公开(公告)号：US20230034585A1
公开(公告)日：2023-02-02
申请号：US17788450
申请日：2020-12-30
申请人： RENERVA, LLC
摘要： Systems, devices, and methods for treating a nerve injury in a patient are provided. The system includes an extracellular matrix, a neutralizing element, and a reconstituting element. The extracellular matrix is configured to promote and/or sustain the growth of tissue and/or associated tissue properties proximate the nerve injury.
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