公开(公告)号：US20230330033A1

公开(公告)日：2023-10-19

申请号：US17907372

申请日：2021-06-07

Applicant: University of Washington

Inventor： Robert Divine ,  Ivan Vulovic ,  David Baker ,  William H. Sheffler ,  Franziska Seeger

IPC: A61K9/51 ,  C07K14/32 ,  C07K16/28

CPC classification number: A61K9/5169 ,  C07K14/32 ,  C07K16/2878 ,  C07K2319/70 ,  C07K2319/30 ,  C07K2317/92

Abstract: Polypeptides are disclosed comprising an (Fc) binding domain, a helical polypeptide monomer, and an oligomer domain, polymers thereof, and uses thereof.

公开(公告)号：US20250049731A1

公开(公告)日：2025-02-13

申请号：US18912238

申请日：2024-10-10

Applicant: University of Washington

Inventor： Robert Divine ,  Ivan Vulovic ,  David Baker ,  William H. Sheffler ,  Franziska Seeger

IPC: A61K9/51 ,  C07K14/32 ,  C07K16/28

Abstract: Polypeptides are disclosed comprising an (Fc) binding domain, a helical polypeptide monomer, and an oligomer domain, polymers thereof, and uses thereof.

公开(公告)号：US20230357323A1

公开(公告)日：2023-11-09

申请号：US18003572

申请日：2021-06-25

Applicant: University of Washington

Inventor： Stephanie Berger ,  Franziska Seeger ,  David Baker ,  Ta-Yi Yu

IPC: C07K14/00 ,  C12N15/63 ,  A61P29/00

CPC classification number: C07K14/001 ,  C12N15/63 ,  A61P29/00

Abstract: The present disclosure provides human 1L-23R (WL-23R) binding polypeptides, conditionally maximally active SilL˜23R binding proteins, multimers thereof, and methods for using the polypeptides and binding proteins for therapeutic use.