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公开(公告)号:US20250051407A1
公开(公告)日:2025-02-13
申请号:US18799107
申请日:2024-08-09
Applicant: University of Washington
Inventor: David Baker , Cameron Glasscock , Robert Pecoraro , Ryan McHugh , Christoffer Norn , Frank DiMaio , David Benjamin Turitz Cox , Brian Coventry , Hugh Haddox , Gyu Rie Lee
Abstract: Polypeptides are provided that include an amino acid sequence at least 50% identical, not including any amino acid insertions at identified insertion sites, to the amino acid sequence selected from the group consisting of SEQ ID NO: 1-52, wherein the polypeptide is a sequence-specific DNA-binding polypeptide, fusion proteins comprising such polypeptides, nucleic acids encoding such polypeptides and fusion proteins, and expression vectors and host cells comprising such nucleic acids.