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公开(公告)号:US20220024942A1
公开(公告)日:2022-01-27
申请号:US17468048
申请日:2021-09-07
发明人: John Frederick TRANT , Daniel MEISTER , Sarah NASR! , Anthony Emanuel CHIFOR , John James HAYWARD , Seyedeh Maryamdokht TAIMOORY , Mohadeseh DASHTI-POUR
IPC分类号: C07D491/18 , C07K1/06
摘要: In a preferred embodiment, there is provided a protecting group for protecting the thiol side chain of a cysteine residue, the protecting group comprising a Diels-Alder cycloadduct of a furan and a maleimide, and optionally, a linker interposed between the thiol side chain and the Diels-Alder cycloadduct.
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公开(公告)号:US20210040105A1
公开(公告)日:2021-02-11
申请号:US16985815
申请日:2020-08-05
发明人: John Frederick TRANT , Daniel MEISTER , Sarah NASRI , Anthony Emanuel CHIFOR , John HAYWARD , Seyedeh Maryamdokht TAIMOORY , Mohadeseh DASHTI-POUR
IPC分类号: C07D491/18 , C07K1/06
摘要: In a preferred embodiment, there is provided a protecting group for protecting the thiol side chain of a cysteine residue, the protecting group comprising a Diels-Alder cycloadduct of a furan and a maleimide, and optionally, a linker interposed between the thiol side chain and the Diels-Alder cycloadduct.
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