公开(公告)号：US20220007997A1

公开(公告)日：2022-01-13

申请号：US17289323

申请日：2019-11-04

Applicant: VANDERBILT UNIVERSITY

Inventor： Emmanuel A. MANNOH ,  Anita MAHADEVAN-JANSEN

IPC: A61B5/00 ,  G01N21/64 ,  G01N21/65 ,  A61B34/20

Abstract: A combined auto-fluorescence imaging and laser speckle contrast imaging (LSCI) system to enable intra-operative parathyroid identification and viability assessment with the same tool. The system includes a light source for emitting a beam of light to illuminate a target of interest, and an imaging head positioned over the target of interest for individually acquiring auto-fluorescence images and LSCI images of light from the illuminated target of interest responsive to the illumination. Auto-fluorescence imaging helps identify the parathyroid, while LSCI helps assess its viability.

公开(公告)号：US20190328309A1

公开(公告)日：2019-10-31

申请号：US16471049

申请日：2017-12-29

Applicant: Vanderbilt University

Inventor： Emmanuel A. MANNOH ,  Anita MAHADEVAN-JANSEN

IPC: A61B5/00 ,  G01N21/65 ,  A61B34/20 ,  G01N21/64

Abstract: One aspect of the invention relates to a method for intraoperative assessment of parathyroid gland viability in a surgery. The method includes diffusing a beam of light onto a tissue surface of a parathyroid gland of a patient to illuminate the tissue surface; acquiring images of the illuminated tissue surface, where each of the acquired images includes a speckle pattern; and processing the acquired images to obtain speckle contrast images for the intraoperative assessment of parathyroid gland viability.