公开(公告)号：US20190022411A1

公开(公告)日：2019-01-24

申请号：US16041636

申请日：2018-07-20

申请人： VARIAN MEDICAL SYSTEMS, INC.

发明人： Renate Parry ,  Eric Abel ,  Swati Girdhani ,  Stanley Mansfield ,  Patrick Kupelian ,  Depak Khuntia

IPC分类号： A61N5/10 ,  A61K9/51 ,  A61P35/00 ,  A61K45/06 ,  G16H20/40

摘要： Methods for treating tumors by administering FLASH radiation and a therapeutic agent to a patient with cancer are disclosed. The methods provide the dual benefits of anti-tumor efficacy plus normal tissue protection when combining therapeutic agents with FLASH radiation to treat cancer patients. The methods described herein also allow for the classification of patients into groups for receiving optimized radiation treatment in combination with a therapeutic agent based on patient-specific biomarker signatures. Also provided are radiation treatment planning methods and systems incorporating FLASH radiation and therapeutic agents.