公开(公告)号：US20240226809A9

公开(公告)日：2024-07-11

申请号：US18547489

申请日：2022-02-23

Applicant: VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY

Inventor： Spencer MARSH ,  Kevin J. PRIDHAM ,  Linda Jane JOURDAN ,  Robert G. GOURDIE

IPC: B01D61/14

CPC classification number: B01D61/14 ,  B01D2311/2676 ,  B01D2315/10 ,  B01D2315/16

Abstract: Described in certain example embodiments herein are methods of isolating exosomes from a biological fluid, such as those containing caseins.

公开(公告)号：US20240131473A1

公开(公告)日：2024-04-25

申请号：US18547489

申请日：2022-02-23

Applicant: VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY

Inventor： Spencer MARSH ,  Kevin J. PRIDHAM ,  Linda Jane JOURDAN ,  Robert G. GOURDIE

IPC: B01D61/14

CPC classification number: B01D61/14 ,  B01D2311/2676 ,  B01D2315/10 ,  B01D2315/16

Abstract: Described in certain example embodiments herein are methods of isolating exosomes from a biological fluid, such as those containing caseins.

公开(公告)号：US20210290539A1

公开(公告)日：2021-09-23

申请号：US17264793

申请日：2019-07-30

Applicant: Robert G. GOURDIE ,  VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. ,  VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY

Inventor： Robert G. GOURDIE ,  L. JANE JOURDAN ,  Eda ROGERS

IPC: A61K9/127 ,  C07K14/705 ,  A61K47/46 ,  A61K9/00 ,  A61P17/02 ,  A61P9/06 ,  A61P25/00 ,  A61P27/02 ,  A23C9/152

Abstract: Described herein are engineered hemichannels, engineered vesicles that can contain the one or more of the engineered hemichannels, pharmaceutical formulations thereof, and uses thereof. In some aspects, the engineered vesicles can include one or more cargo molecules. Also described herein are methods of loading the engineered vesicles. In some aspects, loading of one or more cargo molecules engineered vesicles can be optionally via an engineered hemichannel contained in the engineered vesicle.