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公开(公告)号:US20220144794A1
公开(公告)日:2022-05-12
申请号:US17602133
申请日:2020-04-09
Applicant: Vanderbilt University
Inventor: Gary A. Sulikowski , Christopher Fullenkamp , Kwangho Kim , Somnath Jana
IPC: C07D321/00 , A61P31/04
Abstract: Provided are 9-dechlorochrysophaentin analog compounds and the synthesis process thereof. The disclosed compound have remarkable antimicrobial activities that are comparable to, or even more potent than, the natural product chrysophaentin A. Also provided are method of inhibiting bacterial growth or treating bacterial infection by administering an effective amount of the disclosed compounds.