公开(公告)号：US09028472B2

公开(公告)日：2015-05-12

申请号：US13725894

申请日：2012-12-21

申请人： Vessix Vascular, Inc.

发明人： Prabodh Mathur ,  Rabih Nassif ,  Shahram Moaddeb

IPC分类号： A61B18/04 ,  A61N1/36 ,  A61B18/18 ,  A61B18/14 ,  A61N5/00 ,  A61B18/00 ,  A61B18/12

CPC分类号： A61B18/1492 ,  A61B18/16 ,  A61B18/18 ,  A61B2018/0016 ,  A61B2018/0022 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2018/00577 ,  A61B2018/00654 ,  A61B2018/00678 ,  A61B2018/00767 ,  A61B2018/00791 ,  A61B2018/00815 ,  A61B2018/124 ,  A61N1/05 ,  A61N1/06 ,  A61N1/3606 ,  A61N1/36117 ,  A61N5/00

摘要： Medical devices and methods for making and using the same are disclosed. An example method may include renal-denervation treatment method. The method may include delivering an RF energy treatment to a tissue proximate a renal artery using a catheter assembly of a renal denervation catheter system. The denervation system may include an RF energy generator coupled with the catheter assembly by a controller. The method may also include applying neural activity stimulation to the tissue proximate the renal artery using the catheter assembly, assessing stimulated neural activity response of the tissue using the catheter assembly, and determining a parameter of the RF energy treatment based on the assessed neural activity.

摘要翻译： 公开了用于制造和使用它们的医疗装置和方法。 示例性方法可以包括肾去神经治疗方法。 该方法可以包括使用肾去神经管导管系统的导管组件将RF能量治疗递送到肾动脉附近的组织。 除神经系统可以包括通过控制器与导管组件耦合的RF能量发生器。 该方法还可以包括使用导管组件向肾动脉附近的组织应用神经活动刺激，使用导管组件评估刺激的组织的神经活动反应，以及基于评估的神经活动确定RF能量治疗的参数。

公开(公告)号：US09901738B2

公开(公告)日：2018-02-27

申请号：US14984808

申请日：2015-12-30

申请人： Vessix Vascular, Inc.

发明人： Prabodh Mathur ,  Shahram Moaddeb

IPC分类号： A61B18/14 ,  A61B18/00 ,  A61N1/06 ,  A61N1/05 ,  A61N1/36 ,  A61B18/16 ,  A61B18/18 ,  A61N5/00 ,  A61B18/12

CPC分类号： A61B18/1492 ,  A61B18/16 ,  A61B18/18 ,  A61B2018/0016 ,  A61B2018/0022 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2018/00577 ,  A61B2018/00654 ,  A61B2018/00678 ,  A61B2018/00767 ,  A61B2018/00791 ,  A61B2018/00815 ,  A61B2018/124 ,  A61N1/05 ,  A61N1/06 ,  A61N1/3606 ,  A61N1/36117 ,  A61N5/00

摘要： Medical devices and methods for making and using the same are disclosed. An example method may include a method for treating a patient having congestive heart failure. The method may include positioning an expandable balloon in a renal artery of the patient. The expandable balloon may include a plurality of electrode assemblies. At least some of the electrode assemblies each may include at least two bipolar electrode pairs. The two bipolar electrode pairs may be longitudinally and circumferentially offset from one another. The method may also include expanding the balloon in the renal artery such that at least some of the bipolar electrode pairs are electrically coupled to a wall of the renal artery and energizing at least some of the bipolar electrode pairs so as to therapeutically alter at least one nerve proximate the renal artery to treat the patient's congestive heart failure.

公开(公告)号：US10350005B2

公开(公告)日：2019-07-16

申请号：US15664115

申请日：2017-07-31

申请人： Vessix Vascular, Inc.

发明人： Prabodh Mathur ,  Shahram Moaddeb

IPC分类号： A61N1/05 ,  A61N1/06 ,  A61N1/36 ,  A61N5/00 ,  A61B18/00 ,  A61B18/12 ,  A61B18/14 ,  A61B18/16 ,  A61B18/18

摘要： Medical devices and methods for making and using the same are disclosed. An example method may include a method for treating a patient having congestive heart failure. The method may include positioning an expandable balloon in a renal artery of the patient. The expandable balloon may include a plurality of electrode assemblies. At least some of the electrode assemblies each may include at least two bipolar electrode pairs. The two bipolar electrode pairs may be longitudinally and circumferentially offset from one another. The method may also include expanding the balloon in the renal artery such that at least some of the bipolar electrode pairs are electrically coupled to a wall of the renal artery and energizing at least some of the bipolar electrode pairs so as to therapeutically alter at least one nerve proximate the renal artery to treat the patient's congestive heart failure.

公开(公告)号：US09402684B2

公开(公告)日：2016-08-02

申请号：US13760846

申请日：2013-02-06

申请人： Vessix Vascular, Inc.

发明人： Prabodh Mathur ,  Shahram Moaddeb

IPC分类号： A61B18/14 ,  A61B18/18 ,  A61N1/36 ,  A61N5/00 ,  A61B18/00 ,  A61B18/12

CPC分类号： A61B18/1492 ,  A61B18/16 ,  A61B18/18 ,  A61B2018/0016 ,  A61B2018/0022 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2018/00577 ,  A61B2018/00654 ,  A61B2018/00678 ,  A61B2018/00767 ,  A61B2018/00791 ,  A61B2018/00815 ,  A61B2018/124 ,  A61N1/05 ,  A61N1/06 ,  A61N1/3606 ,  A61N1/36117 ,  A61N5/00

摘要： Medical devices and methods for making and using the same are disclosed. An example method may include a method for treating a patient having congestive heart failure. The method may include positioning an expandable balloon in a renal artery of the patient. The expandable balloon may include a plurality of electrode assemblies. At least some of the electrode assemblies each may include at least two bipolar electrode pairs. The two bipolar electrode pairs may be longitudinally and circumferentially offset from one another. The method may also include expanding the balloon in the renal artery such that at least some of the bipolar electrode pairs are electrically coupled to a wall of the renal artery and energizing at least some of the bipolar electrode pairs so as to therapeutically alter at least one nerve proximate the renal artery to treat the patient's congestive heart failure.

摘要翻译： 公开了用于制造和使用它们的医疗装置和方法。 示例性方法可以包括用于治疗患有充血性心力衰竭的患者的方法。 该方法可以包括将可扩张气囊定位在患者的肾动脉中。 可膨胀气囊可以包括多个电极组件。 至少一些电极组件每个可以包括至少两个双极电极对。 两个双极电极对可以在纵向上和周向地彼此偏移。 该方法还可以包括扩大肾动脉中的气囊，使得至少一些双极性电极对电耦合到肾动脉的壁并激励至少一些双极性电极对，以便治疗性地改变至少一个 靠近肾动脉的神经，以治疗患者的充血性心力衰竭。