公开(公告)号：US06403636B1

公开(公告)日：2002-06-11

申请号：US09605650

申请日：2000-06-28

申请人： Vichai Reutrakul ,  Thaiwatchai Santisuk ,  Gerhard Noessner ,  Juergen Schmidt ,  Bernd Nickel ,  Thomas Klenner ,  Sebastian Hose

发明人： Vichai Reutrakul ,  Thaiwatchai Santisuk ,  Gerhard Noessner ,  Juergen Schmidt ,  Bernd Nickel ,  Thomas Klenner ,  Sebastian Hose

IPC分类号： A61K31352

CPC分类号： C07D493/20

摘要： This invention relates to novel xanthone compounds, their preparation and use as medicament. More particularly this invention is directed to the isolation of the novel xanthone natural product sootepenseone from Dasymaschalon sootepense Craib, Annonaceae, its identification and derivatization, and the use of sootepenseone and its derivatives as anticancer agents.

摘要翻译： 本发明涉及新型的呫吨酮化合物，其制备和作为药物的用途。 更具体地，本发明涉及从Dasymaschalon sootepense Craib，Annonaceae分离出新型呫吨酮天然产物白藜芦酮，其鉴定和衍生化，以及使用烟灰one素及其衍生物作为抗癌剂。