Matched filtration with experimental noise determination for denoising, peak picking and quantitation in LC-MS
    1.
    发明授权
    Matched filtration with experimental noise determination for denoising, peak picking and quantitation in LC-MS 失效
    在LC-MS中进行去噪,峰值采集和定量的实验噪声测定的匹配滤波

    公开(公告)号:US07409298B2

    公开(公告)日:2008-08-05

    申请号:US10510992

    申请日:2003-04-11

    IPC分类号: G01N31/00

    摘要: An improved system and method of analyzing sample data that increases the reliability of peak (compound) detection and identification in the presence of chemical and/or random noise. The sample analysis system includes a compound-separating unit for separating constituent compounds in a sample mixture, a compound-analyzing unit for identifying and quantitating at least one of the separated compounds, and a computer for acquiring data from the compound-separating and compound-analyzing units, for generating a multi-dimensional data set incorporating the acquired data, for executing an algorithm for reducing noise in the data set and for detecting peaks (compounds) in the noise-reduced data set, and for identifying/quantitating the detected compounds.

    摘要翻译: 一种改进的系统和方法,用于分析样本数据,提高在存在化学和/或随机噪声的情况下峰(复合)检测和识别的可靠性。 样品分析系统包括用于分离样品混合物中的组分化合物的化合物分离单元,用于鉴定和定量分离的化合物中的至少一种的化合物分析单元,以及用于从化合物分离和化合物分离单元中获取数据的计算机, 分析单元,用于生成包含所获取的数据的多维数据集,用于执行用于减少数据集中的噪声并且用于检测噪声减小的数据集中的峰值(化合物)的算法,以及用于识别/定量检测到的化合物 。