专利检索 ap:("ViiV HEALTHCARE UK (NO.5) LIMITED") AND inv:"Ira B. DICKER" 第 1 页

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发明申请
C-3 AND C-17 MODIFIED TRITERPENOIDS AS HIV-1 INHIBITORS 审中-公开

公开(公告)号：US20190031709A1

公开(公告)日：2019-01-31

申请号：US16071925

申请日：2017-02-02

申请人： ViiV HEALTHCARE UK (NO.5) LIMITED

发明人： Jie CHEN , Yan CHEN , Ira B. DICKER , Richard A. HARTZ , Nicholas A. MEANWELL , Beata NOWICKA-SANS , Alicia REGUEIRO-REN , Sing-Yuen SIT , Ny SIN , Jacob SWIDORSKI , Brian Lee VENABLES

IPC分类号： C07J53/00 , A61P31/18

CPC分类号： C07J53/002 , A61P31/18 , C07J63/008 , C12N9/506 , C12N2740/16222

摘要： Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, betulinic acid derivatives that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formula I: These compounds are useful for the treatment of HIV and AIDS.