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公开(公告)号:US20230137343A1
公开(公告)日:2023-05-04
申请号:US17938545
申请日:2022-10-06
发明人: Kathleen BOYLE , Hangil PARK , Srinivas KOTHAKOTA , Mark SELBY , Thomas BRENNAN , Lewis T. WILLIAMS , Rosa Romano , Weijie Lan
摘要: The present invention relates to methods and combination therapies for enhancing the activity and function of non-B cell immune cells (such as T cells) using genetically modified B cells. These methods and combinations can be used, for example, for the treatment of a variety of diseases and disorders, including cancer, heart disease, inflammatory disease, muscle wasting disease, neurological disease, and the like.