公开(公告)号：US10962528B2

公开(公告)日：2021-03-30

申请号：US16065277

申请日：2016-12-20

Applicant: WISYS TECHNOLOGY FOUNDATION, INC.

Inventor： Ramaswamy Subramanian ,  Swagatha Ghosh ,  Wayne Ford Schaefer

IPC: C07K14/46 ,  C07K14/435 ,  C07K14/00 ,  G01N33/533 ,  G01N33/566 ,  G01N33/53

Abstract: Provided herein are monomeric variants of Sandercyanin fluorescent protein (SFP) including those monomeric SFP variants set forth in SEQ ID NO:2-6 and SFP variants with increased brightness. Also provided herein are methods of making and using fluorescent probes comprising such monomeric variants, where the fluorescent probes have specificity for desired targets.