公开(公告)号：US20220403023A1

公开(公告)日：2022-12-22

申请号：US17770039

申请日：2020-10-23

申请人： WUXI BIOLOGICS IRELAND LIMITED

发明人： Qin MEI ,  Fagen HU ,  Jing LI ,  Jiaxiang SHAO ,  Yuhong SHEN

IPC分类号： C07K16/28 ,  A61P35/00 ,  A61K39/395 ,  A61K45/06

摘要： Provided are anti-CD47 antibodies, the nucleic acid molecules encoding the anti-CD47 antibodies, expression vectors and host cells used for the expression of anti-CD47 antibodies. Provided are methods for validating the function of antibodies. The antibodies provide a potent agent for the treatment of cancers via modulating immune functions.