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1.发明申请Blood and tissue sample assessment of mitochondrial function and biochemistry as a tool for selection for feed efficiency and other production parameters 审中-公开血液和组织样品评估线粒体功能和生物化学作为选择饲料效率和其他生产参数的工具公开(公告)号：US20060154255A1
公开(公告)日：2006-07-13
申请号：US10745874
申请日：2003-12-27
申请人： Walter Bottje , Neil Pumford , Ron Okimoto , Mohammad Iqbal
发明人： Walter Bottje , Neil Pumford , Ron Okimoto , Mohammad Iqbal
CPC分类号： G01N33/53
摘要： The present invention provides methods for predicting feed efficiency in animals by correlating the association of mitochondrial function with feed efficiency. In one embodiment, the invention provides a method for determining feed efficiency comprising comparing proteins patterns and activity levels with antibody interaction of proteins associated with mitochondrial function and feed efficiency. In an alternative embodiment, the present invention also provides methods for predicting feed efficiency in animals by identifying animals having genetic mutations or polymorphisms that are associated with mitochondrial function and feed efficiency.
摘要翻译： 本发明提供了通过将线粒体功能与饲料效率的关联相关联来预测动物饲料效率的方法。 在一个实施方案中，本发明提供了一种用于确定饲料效率的方法，其包括将蛋白质模式和活性水平与与线粒体功能和饲料效率相关的蛋白质的抗体相互作用进行比较。 在替代实施方案中，本发明还提供了通过鉴定具有与线粒体功能和饲料效率相关的基因突变或多态性的动物来预测动物饲料效率的方法。
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2.发明申请COMPOSITIONS AND METHODS FOR INCREASING HEALTH AND REDUCING PATHOGENIC BACTERIA IN ANIMALS 审中-公开增加动物健康和减少病原菌的组合物和方法公开(公告)号：US20130017174A1
公开(公告)日：2013-01-17
申请号：US13547790
申请日：2012-07-12
申请人： Billy Hargis , Neil Pumford , Amanda Wolfenden
发明人： Billy Hargis , Neil Pumford , Amanda Wolfenden
CPC分类号： A61K35/744 , A61K33/00 , A61K35/74 , A61K2300/00
摘要： Probiotic compositions comprising a bacterium that is capable of producing nitric oxide and a substrate of nitric oxide synthase are provided. Also provided are methods of improving the gastrointestinal health of a subject by orally administering a bacterium capable of producing nitric oxide and orally administering a substrate of nitric oxide synthase. Methods of reducing the inflammatory immune response after treatment with a probiotic and methods of reducing horizontal transmission of pathogenic bacteria within groups of animals are also provided.
摘要翻译： 提供了包含能够产生一氧化氮的细菌和一氧化氮合成酶底物的益生菌组合物。 还提供了通过口服施用能够产生一氧化氮并口服一氧化氮合酶底物的细菌来改善受试者的胃肠健康的方法。 还提供了在用益生菌治疗后减少炎症免疫应答的方法以及减少动物群内致病细菌横向传播的方法。
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