Rapid antimicrobial susceptibility testing using piezoelectric sensor

    公开(公告)号:US10670566B2

    公开(公告)日:2020-06-02

    申请号:US15777750

    申请日:2016-11-18

    摘要: A system for and method of antimicrobial susceptibility testing includes detecting a resonance peak of a sensor provided with live microbes on a surface thereof; applying a substance to the live microbes; detecting a resonance peak of said sensor after application of said substance; determining a width of a top of each of said resonance peaks before and after application of the substance from one of: (1) a phase angle versus frequency plot where the phase angle is the phase angle of the electrical impedance of said sensor. (2) a real part of a plot of an electrical impedance versus frequency of said sensor. (3) a plot of a magnitude of electrical impedance versus frequency of said sensor, and (4) a phase angle versus frequency plot where the phase angle is the phase angle between an output voltage and an input voltage of said sensor, and comparing the determined widths of tops of said resonance peaks or standard deviations of the frequency of said resonance peaks to determine antimicrobial susceptibility including the minimum inhibitory concentration (MIC).

    Method and system to perform energy-extraction based active noise control

    公开(公告)号:US20060064180A1

    公开(公告)日:2006-03-23

    申请号:US10731742

    申请日:2003-12-09

    IPC分类号: G05B13/02

    CPC分类号: G05B13/042 G10K11/178

    摘要: A method to provide active noise control to reduce noise and vibration in reverberant acoustic enclosures such as aircraft, vehicles, appliances, instruments, industrial equipment and the like is presented. A continuous-time multi-input multi-output (MIMO) state space mathematical model of the plant is obtained via analytical modeling and system identification. Compensation is designed to render the mathematical model passive in the sense of mathematical system theory. The compensated system is checked to ensure robustness of the passive property of the plant. The check ensures that the passivity is preserved if the mathematical model parameters are perturbed from nominal values. A passivity-based controller is designed and verified using numerical simulations and then tested. The controller is designed so that the resulting closed-loop response shows the desired noise reduction.