公开(公告)号：US07079897B2

公开(公告)日：2006-07-18

申请号：US10839875

申请日：2004-05-06

申请人： Weimin Sun ,  Bruce R. Jones ,  Douglas J. Lang ,  Donald Hopper

发明人： Weimin Sun ,  Bruce R. Jones ,  Douglas J. Lang ,  Donald Hopper

IPC分类号： A61N1/18

CPC分类号： A61N1/365 ,  A61N1/36585

摘要： A system and method for automatically adjusting the operating parameters of a rate-adaptive cardiac pacemaker. In accordance with the method, maximum exertion levels attained by the patient are measured at periodic intervals and stored. The stored maximum exertion levels may then be used to update a long-term maximal exertion level, and the slope of the rate-response curve is adjusted to map the updated long-term maximal exertion level to a maximum allowable pacing rate. The stored maximum exertion levels may also be used to update a sensor target rate which is used to adjust the slope of the rate response curve.

公开(公告)号：US06839593B1

公开(公告)日：2005-01-04

申请号：US09657404

申请日：2000-09-08

申请人： Weimin Sun ,  Bruce R. Jones ,  Douglas J. Lang ,  Donald Hopper

发明人： Weimin Sun ,  Bruce R. Jones ,  Douglas J. Lang ,  Donald Hopper

IPC分类号： A61N1/18 ,  A61N1/365

CPC分类号： A61N1/365

摘要： A system and method for automatically adjusting the operating parameters of a rate-adaptive cardiac pacemaker in which maximum exertion levels attained by the patient are measured at periodic intervals and stored. The stored maximum exertion levels may then be used to update a long-term maximal exertion level, and the slope of the rate-response curve is adjusted to map the updated long-term maximal exertion level to a maximum allowable pacing rate. In accordance with the invention, the rate response curve is defined such that an exertion level corresponding to the patient's maximum exercise capacity would be mapped to a physiologically favorable maximum rate that is independent from a specified maximum sensor indicated rate.

摘要翻译： 用于自动调整速率自适应心脏起搏器的操作参数的系统和方法，其中以周期性间隔测量由患者达到的最大消耗水平并被存储。 然后可以使用存储的最大消耗水平来更新长期最大消耗水平，并且调整速率 - 响应曲线的斜率以将更新的长期最大消耗水平映射到最大允许起搏速率。 根据本发明，速率响应曲线被定义为使得与患者的最大运动能力相对应的运动水平将被映射到独立于指定的最大传感器指示速率的生理上有利的最大速率。

公开(公告)号：US20120004696A1

公开(公告)日：2012-01-05

申请号：US13230563

申请日：2011-09-12

申请人： Weimin Sun ,  Bruce R. Jones ,  Douglas J. Lang ,  Donald Hopper

发明人： Weimin Sun ,  Bruce R. Jones ,  Douglas J. Lang ,  Donald Hopper

IPC分类号： A61N1/365

CPC分类号： A61N1/365 ,  A61N1/36585

摘要： A system and method for automatically adjusting the operating parameters of a rate-adaptive cardiac pacemaker. In accordance with the method, maximum exertion levels attained by the patient are measured at periodic intervals and stored. The stored maximum exertion levels may then be used to update a long-term maximal exertion level, and the slope of the rate-response curve is adjusted to map the updated long-term maximal exertion level to a maximum allowable pacing rate. The stored maximum exertion levels may also be used to update a sensor target rate which is used to adjust the slope of the rate response curve.

摘要翻译： 一种用于自动调整速率适应性心脏起搏器的操作参数的系统和方法。 按照该方法，以周期性的间隔测量患者获得的最大功耗水平并存储。 然后可以使用存储的最大消耗水平来更新长期最大消耗水平，并且调整速率 - 响应曲线的斜率以将更新的长期最大消耗水平映射到最大允许起搏速率。 存储的最大消耗电平也可用于更新用于调整速率响应曲线的斜率的传感器目标速率。

公开(公告)号：US06823214B1

公开(公告)日：2004-11-23

申请号：US09657402

申请日：2000-09-08

申请人： Weimin Sun ,  Bruce R. Jones ,  Douglas J. Lang ,  Donald Hopper

发明人： Weimin Sun ,  Bruce R. Jones ,  Douglas J. Lang ,  Donald Hopper

IPC分类号： A61N118

CPC分类号： A61N1/365 ,  A61N1/36585

摘要： A system and method for automatically adjusting the operating parameters of a rate-adaptive cardiac pacemaker. In accordance with the method, maximum exertion levels attained by the patient are measured at periodic intervals and stored. The stored maximum exertion levels may then be used to update a long-term maximal exertion level, and the slope of the rate-response curve is adjusted to map the updated long-term maximal exertion level to a maximum allowable pacing rate. The stored maximum exertion levels may also be used to update a sensor target rate which is used to adjust the slope of the rate response curve.

摘要翻译： 一种用于自动调整速率适应性心脏起搏器的操作参数的系统和方法。 按照该方法，以周期性的间隔测量患者获得的最大功耗水平并存储。 然后可以使用存储的最大消耗水平来更新长期最大消耗水平，并且调整速率 - 响应曲线的斜率以将更新的长期最大消耗水平映射到最大允许起搏速率。 存储的最大消耗电平也可用于更新用于调整速率响应曲线的斜率的传感器目标速率。

公开(公告)号：US07567839B2

公开(公告)日：2009-07-28

申请号：US11457382

申请日：2006-07-13

申请人： Weimin Sun ,  Bruce R. Jones ,  Douglas J. Lang ,  Donald Hopper

发明人： Weimin Sun ,  Bruce R. Jones ,  Douglas J. Lang ,  Donald Hopper

IPC分类号： A61N1/18

CPC分类号： A61N1/365 ,  A61N1/36585

摘要： A system and method for automatically adjusting the operating parameters of a rate-adaptive cardiac pacemaker. In accordance with the method, maximum exertion levels attained by the patient are measured at periodic intervals and stored. The stored maximum exertion levels may then be used to update a long-term maximal exertion level, and the slope of the rate-response curve is adjusted to map the updated long-term maximal exertion level to a maximum allowable pacing rate. The stored maximum exertion levels may also be used to update a sensor target rate which is used to adjust the slope of the rate response curve.

摘要翻译： 一种用于自动调整速率适应性心脏起搏器的操作参数的系统和方法。 按照该方法，以周期性的间隔测量患者获得的最大功耗水平并存储。 然后可以使用存储的最大消耗水平来更新长期最大消耗水平，并且调整速率 - 响应曲线的斜率以将更新的长期最大消耗水平映射到最大允许起搏速率。 存储的最大消耗电平也可用于更新用于调整速率响应曲线的斜率的传感器目标速率。

公开(公告)号：US08494632B2

公开(公告)日：2013-07-23

申请号：US13230563

申请日：2011-09-12

申请人： Weimin Sun ,  Bruce R. Jones ,  Douglas J. Lang ,  Donald L. Hopper

发明人： Weimin Sun ,  Bruce R. Jones ,  Douglas J. Lang ,  Donald L. Hopper

IPC分类号： A61N1/18

CPC分类号： A61N1/365 ,  A61N1/36585

摘要： A system and method for automatically adjusting the operating parameters of a rate-adaptive cardiac pacemaker. In accordance with the method, maximum exertion levels attained by the patient are measured at periodic intervals and stored. The stored maximum exertion levels may then be used to update a long-term maximal exertion level, and the slope of the rate-response curve is adjusted to map the updated long-term maximal exertion level to a maximum allowable pacing rate. The stored maximum exertion levels may also be used to update a sensor target rate which is used to adjust the slope of the rate response curve.

公开(公告)号：US08019418B2

公开(公告)日：2011-09-13

申请号：US12507414

申请日：2009-07-22

申请人： Weimin Sun ,  Bruce R. Jones ,  Douglas J. Lang ,  Donald L. Hopper

发明人： Weimin Sun ,  Bruce R. Jones ,  Douglas J. Lang ,  Donald L. Hopper

IPC分类号： A61N1/18

CPC分类号： A61N1/365 ,  A61N1/36585

摘要： A system and method for automatically adjusting the operating parameters of a rate-adaptive cardiac pacemaker. In accordance with the method, maximum exertion levels attained by the patient are measured at periodic intervals and stored. The stored maximum exertion levels may then be used to update a long-term maximal exertion level, and the slope of the rate-response curve is adjusted to map the updated long-term maximal exertion level to a maximum allowable pacing rate. The stored maximum exertion levels may also be used to update a sensor target rate which is used to adjust the slope of the rate response curve.

摘要翻译： 一种用于自动调整速率适应性心脏起搏器的操作参数的系统和方法。 按照该方法，以周期性的间隔测量患者获得的最大功耗水平并存储。 然后可以使用存储的最大消耗水平来更新长期最大消耗水平，并且调整速率 - 响应曲线的斜率以将更新的长期最大消耗水平映射到最大允许起搏速率。 存储的最大消耗电平也可用于更新用于调整速率响应曲线的斜率的传感器目标速率。

公开(公告)号：US20090287270A1

公开(公告)日：2009-11-19

申请号：US12507414

申请日：2009-07-22

申请人： Weimin Sun ,  Bruce R. Jones ,  Douglas J. Lang ,  Donald L. Hopper

发明人： Weimin Sun ,  Bruce R. Jones ,  Douglas J. Lang ,  Donald L. Hopper

IPC分类号： A61N1/365

CPC分类号： A61N1/365 ,  A61N1/36585

摘要： A system and method for automatically adjusting the operating parameters of a rate-adaptive cardiac pacemaker. In accordance with the method, maximum exertion levels attained by the patient are measured at periodic intervals and stored. The stored maximum exertion levels may then be used to update a long-term maximal exertion level, and the slope of the rate-response curve is adjusted to map the updated long-term maximal exertion level to a maximum allowable pacing rate. The stored maximum exertion levels may also be used to update a sensor target rate which is used to adjust the slope of the rate response curve.

摘要翻译： 一种用于自动调整速率适应性心脏起搏器的操作参数的系统和方法。 按照该方法，以周期性的间隔测量患者获得的最大功耗水平并存储。 然后可以使用存储的最大消耗水平来更新长期最大消耗水平，并且调整速率 - 响应曲线的斜率以将更新的长期最大消耗水平映射到最大允许起搏速率。 存储的最大消耗电平也可用于更新用于调整速率响应曲线的斜率的传感器目标速率。

公开(公告)号：US07493163B2

公开(公告)日：2009-02-17

申请号：US11461632

申请日：2006-08-01

申请人： Weimin Sun ,  Bruce R. Jones ,  Douglas J. Lang

发明人： Weimin Sun ,  Bruce R. Jones ,  Douglas J. Lang

IPC分类号： A61N1/365

CPC分类号： A61N1/36585

摘要： A method and system for automatically adjusting the operating parameters of a rate-adaptive cardiac pacemaker in which maximum exertion levels attained by the patient are measured at periodic intervals and stored in order to compute or update a maximum exercise capacity. The slope of the rate-response curve is then adjusted to map an exertion level corresponding to the updated maximum exercise capacity to a maximum allowable pacing rate. In accordance with the invention, a maximum exercise capacity is determined by cross-checking periodic maximum exertion level sensor values with a motion-level sensor value.

摘要翻译： 一种用于自动调整速率自适应心脏起搏器的操作参数的方法和系统，其中以周期性间隔测量由患者获得的最大消耗水平并存储以便计算或更新最大运动能力。 然后调整速率 - 响应曲线的斜率以将对应于更新的最大运动能力的运动水平映射到最大允许起搏速率。 根据本发明，通过用运动水平传感器值交叉检查周期性最大消耗水平传感器值来确定最大运动能力。

公开(公告)号：US06519495B1

公开(公告)日：2003-02-11

申请号：US09638975

申请日：2000-08-15

申请人： Weimin Sun ,  Bruce R. Jones ,  Douglas J. Lang

发明人： Weimin Sun ,  Bruce R. Jones ,  Douglas J. Lang

IPC分类号： A61N136

CPC分类号： A61N1/36585

摘要： A method and system for automatically adjusting the operating parameters of a rate-adaptive cardiac pacemaker in which maximum exertion levels attained by the patient are measured at periodic intervals and stored in order to compute or update a maximum exercise capacity. The slope of the rate-response curve is then adjusted to map an exertion level corresponding to the updated maximum exercise capacity to a maximum allowable pacing rate. In accordance with the invention, a maximum exercise capacity is determined by cross-checking periodic maximum exertion level sensor values with a motion-level sensor value.