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公开(公告)号：US20080038829A1
公开(公告)日：2008-02-14
申请号：US11628168
申请日：2005-06-01
申请人： Werner Kremer , Hans Kalbitzer , Fritz Huber
发明人： Werner Kremer , Hans Kalbitzer , Fritz Huber
CPC分类号： G01N24/08 , G01R33/4625 , G01R33/465 , Y10T436/24
摘要： The invention describes a process for the determination of the concentration distribution and size distribution of lipoprotein classes in body fluids, e.g. blood. For this purpose, NMR spectra of a sample to be analysed are measured by magnetic field gradient intensities and temperatures under different diffusion-weighted measuring conditions selected according to different pulse programs (e.g. PFG-STE, PFG-LED etc) and consequently in a differentiated manner according to the relaxation times. The different effects of these measuring conditions on the intensity/line form of the NMR signals of the individual lipoprotein classes are determined and permit the determination of a concentration distribution/size distribution of the individual lipoprotein classes.
摘要翻译： 本发明描述了用于测定体液中脂蛋白类别的浓度分布和尺寸分布的方法，例如， 血液。 为此，通过根据不同脉冲程序选择的不同扩散加权测量条件下的磁场梯度强度和温度来测量要分析的样品的NMR谱（例如PFG-STE，PFG-LED等），并因此分化 方式根据放松时间。 确定这些测量条件对各个脂蛋白类别的NMR信号的强度/线形式的不同影响，并且允许测定各个脂蛋白类别的浓度分布/尺寸分布。
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公开(公告)号：US07927878B2
公开(公告)日：2011-04-19
申请号：US11628168
申请日：2005-06-01
CPC分类号： G01N24/08 , G01R33/4625 , G01R33/465 , Y10T436/24
摘要： The invention describes a process for the determination of the concentration distribution and size distribution of lipoprotein classes in body fluids, e.g. blood. For this purpose, NMR spectra of a sample to be analysed are measured by magnetic field gradient intensities and temperatures under different diffusion-weighted measuring conditions selected according to different pulse programs (e.g. PFG-STE, PFG-LED etc) and consequently in a differentiated manner according to the relaxation times. The different effects of these measuring conditions on the intensity/line form of the NMR signals of the individual lipoprotein classes are determined and permit the determination of a concentration distribution/size distribution of the individual lipoprotein classes.
摘要翻译： 本发明描述了用于测定体液中脂蛋白类别的浓度分布和尺寸分布的方法，例如， 血液。 为此，通过根据不同脉冲程序选择的不同扩散加权测量条件下的磁场梯度强度和温度来测量要分析的样品的NMR谱（例如PFG-STE，PFG-LED等），并因此分化 方式根据放松时间。 确定这些测量条件对各个脂蛋白类别的NMR信号的强度/线形式的不同影响，并且允许测定各个脂蛋白类别的浓度分布/尺寸分布。
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公开(公告)号：US20130289887A1
公开(公告)日：2013-10-31
申请号：US13878094
申请日：2011-10-05
申请人： Fritz Huber , Renate Kirchhoefer , Volker Pfahlert
发明人： Fritz Huber , Renate Kirchhoefer , Volker Pfahlert
IPC分类号： G06F19/10
CPC分类号： G16B99/00 , G01N24/08 , G01R33/4625 , G16B40/00
摘要： The invention relates to a method for characterizing a sample, having the following steps: providing at least one analysis result having a plurality of values, wherein the analysis result was generated by the analysis of a sample by at least one analysis method; determining the value of at least one mathematic relation between at least two values of the plurality of values; generating a characterizing signature of the sample on the basis of the value of the at least one mathematic relation. The invention further relates to a method for characterizing a system in which method the preceding method is used.
摘要翻译： 本发明涉及一种用于表征样品的方法，具有以下步骤：提供具有多个值的至少一个分析结果，其中通过至少一种分析方法对样品进行分析而产生分析结果; 确定所述多个值中的至少两个值之间的至少一个数学关系的值; 基于所述至少一个数学关系的值生成所述样本的表征特征。 本发明还涉及一种用于表征其中使用前述方法的方法的系统的方法。
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