公开(公告)号：US10258744B2

公开(公告)日：2019-04-16

申请号：US14758042

申请日：2013-04-05

申请人： West Pharmaceutical Services, Inc.

发明人： Jeffrey M. Laubach ,  Jurgen Brinkhues ,  Heike Gruen ,  Joel Worman ,  Xia Zhao ,  Jason Mattia

IPC分类号： A61M5/315

摘要： A pharmaceutical syringe piston having a longitudinal axis includes a body having a central face portion with a first outer circumference and maximum first diameter. A cylindrical sealing portion proximate the central face portion has first and second axial ends and a wall extending therebetween. The wall has a second outer circumference and a second diameter essentially constant along the longitudinal axis between the first and second axial ends of the cylindrical sealing portion and is larger than the maximum first diameter. An annular curved portion has a maximum outer diameter less than the second diameter and connects the first axial end of the cylindrical sealing portion to the first outer circumference. An inert film encloses the central face portion and at least a part of the annular curved portion and has an outer boundary between the first axial end of the cylindrical sealing portion and the first outer circumference.

公开(公告)号：US11607498B2

公开(公告)日：2023-03-21

申请号：US17828055

申请日：2022-05-31

申请人： West Pharmaceutical Services, Inc.

发明人： Jeffrey M. Laubach ,  Jurgen Brinkhues ,  Heike Gruen ,  Joel Worman ,  Xia Zhao ,  Jason Mattia

IPC分类号： A61M5/315

摘要： A piston to be provided within an inner wall of a barrel of a pharmaceutical syringe for dispensing medicament retained in the barrel is described. The piston includes a body defining a central face, a cylindrical portion, and an annular curved portion between the cylindrical portion and the central face portion. The piston also includes an inert film enclosing the central face portion and at least a part of the annular curved portion. The cylindrical portion and the part of the annular curved portion are together configured to maintain a fluid-tight seal with the inner wall of the barrel. A pharmaceutical syringe is described for dispensing a medicament includes a barrel configured to retain the medicament and the piston.

公开(公告)号：US11951289B2

公开(公告)日：2024-04-09

申请号：US17828046

申请日：2022-05-31

申请人： West Pharmaceutical Services, Inc.

发明人： Jeffrey M. Laubach ,  Jurgen Brinkhues ,  Heike Gruen ,  Joel Worman ,  Xia Zhao ,  Jason Mattia

IPC分类号： A61M5/315

CPC分类号： A61M5/31513 ,  A61M2205/0222

摘要： A piston having a longitudinal axis and opposing proximal and distal axial ends is manufactured by a method including molding a partially formed piston body and then molding the piston. The partially formed piston body is molded by placing a first rubber sheet and an inert film between die plates of a first forming tool, vulcanizing the first rubber sheet and the inert film between the die plates of the first forming tool, and blanking out the partially formed piston body from the first rubber sheet and the inert film. The piston is then molded by placing the partially formed piston body into a second forming tool, placing a second rubber sheet into the second forming tool, vulcanizing the second rubber sheet and the partially formed piston body together, and blanking out the piston from the second rubber sheet at a trim edge spaced apart from the inert film.

公开(公告)号：US11369742B2

公开(公告)日：2022-06-28

申请号：US16354675

申请日：2019-03-15

申请人： West Pharmaceutical Services, Inc.

发明人： Jeffrey M. Laubach ,  Jurgen Brinkhues ,  Heike Gruen ,  Joel Worman ,  Xia Zhao ,  Jason Mattia

IPC分类号： A61M5/315

摘要： A pharmaceutical syringe piston having a longitudinal axis includes a body having a central face portion with a first outer circumference and maximum first diameter. A cylindrical sealing portion proximate the central face portion has first and second axial ends and a wall extending therebetween. The wall has a second outer circumference and a second diameter essentially constant along the longitudinal axis between the first and second axial ends of the cylindrical sealing portion and is larger than the maximum first diameter. An annular curved portion has a maximum outer diameter less than the second diameter and connects the first axial end of the cylindrical sealing portion to the first outer circumference. An inert film encloses the central face portion and at least part of the annular curved portion and has an outer boundary between the first axial end of the cylindrical sealing portion and the first outer circumference.