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公开(公告)号:US09034857B2
公开(公告)日:2015-05-19
申请号:US13636785
申请日:2011-03-24
申请人: William C. Burhans , Catherine E. Prudom Gineste , Christopher P. Allen , Oleg Ursu , Anna Waller , Larry A. Sklar
发明人: William C. Burhans , Catherine E. Prudom Gineste , Christopher P. Allen , Oleg Ursu , Anna Waller , Larry A. Sklar
IPC分类号: A61K31/498 , A61K31/58 , A61K31/56 , C12Q1/02
CPC分类号: A61K31/58 , A61K31/498 , A61K31/56 , C12Q1/025 , G01N2500/10 , G01N2800/7009
摘要: Provided are methods and compositions for reducing superoxide anions such that a prophylactic or therapeutic effect against conditions associated with excess oxidative stress achieved. The compositions and methods provide for reducing inflammation and for enhancing lifespan of eukaryotic organisms. A screen for identifying compounds that can be used in these methods is also provided.
摘要翻译: 提供了用于减少超氧化物阴离子的方法和组合物,使得针对与过量氧化应激相关的病症达到预防或治疗效果。 组合物和方法提供减少炎症并增加真核生物的寿命。 还提供了用于鉴定可用于这些方法中的化合物的筛选。
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公开(公告)号:US20130150336A1
公开(公告)日:2013-06-13
申请号:US13636785
申请日:2011-03-24
申请人: WIlliam C. Burhans , Catherine E. Prudom , Christopher P. Allen , Oleg Ursu , Anna Waller , Larry A. Sklar
发明人: WIlliam C. Burhans , Catherine E. Prudom , Christopher P. Allen , Oleg Ursu , Anna Waller , Larry A. Sklar
CPC分类号: A61K31/58 , A61K31/498 , A61K31/56 , C12Q1/025 , G01N2500/10 , G01N2800/7009
摘要: Provided are methods and compositions for reducing superoxide anions such that a prophylactic or therapeutic effect against conditions associated with excess oxidative stress achieved. The compositions and methods provide for reducing inflammation and for enhancing lifespan of eukaryotic organisms. A screen for identifying compounds that can be used in these methods is also provided.
摘要翻译: 提供了用于减少超氧化物阴离子的方法和组合物,使得针对与过量氧化应激相关的病症达到预防或治疗效果。 组合物和方法提供减少炎症并增加真核生物的寿命。 还提供了用于鉴定可用于这些方法中的化合物的筛选。
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