专利检索 ap:("William Kelly, deceased" OR "by John Kelly, joint personal representative" OR "Alfred Halpern") AND inv:"by John Kelly, joint personal representative" 第 1 页

1.

发明授权
Preparation of alkali metal choline salicylate salt complexes 失效
标题翻译：碱金属醇盐盐酸盐复合物的制备

公开(公告)号：US4098813A

公开(公告)日：1978-07-04

申请号：US753396

申请日：1976-12-22

申请人： William Kelly, deceased , by John Kelly, joint personal representative , Alfred Halpern

发明人： William Kelly, deceased , by John Kelly, joint personal representative , Alfred Halpern

IPC分类号： A61K47/02 , C07C91/00

CPC分类号： A61K47/02

摘要： Choline salicylate sulfite and choline salicylate alkali metal sulfite-containing compounds of the formula, ##STR1## WHEREIN Me represents the sodium, potassium or lithium ion and R represents the sulfite, bisulfite, metabisulfite, dithionate, hydrosulfite and hyposulfite groups are described. Said compounds are stable and inhibit the formation of color in pharmaceutical preparations containing the same. The method for the preparation of choline salicylate sulfite and choline salicylate alkali metal sulfite-containing compounds, and pharmaceutical dosage forms containing the same are disclosed together with a method for their use to inhibit color formation.