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1.Synthesis of piperidine and piperazine compounds as CCR5 antagonists 审中-公开
标题翻译: 哌啶和哌嗪化合物作为CCR5拮抗剂的合成公开(公告)号:US20050187248A1
公开(公告)日:2005-08-25
申请号:US11088585
申请日:2005-03-24
申请人: William Leong , Minzhang Chen , Bosco D'sa , Man Zhu , Tong Xiao , Xiongwei Shi , Suhan Tang , Dinesh Gala , Andrew Goodman , Christopher Nielsen , Gary Lee , Juan Gamboa , Andrew Jones
发明人: William Leong , Minzhang Chen , Bosco D'sa , Man Zhu , Tong Xiao , Xiongwei Shi , Suhan Tang , Dinesh Gala , Andrew Goodman , Christopher Nielsen , Gary Lee , Juan Gamboa , Andrew Jones
IPC分类号: A61K31/4545 , A61P11/06 , A61P17/02 , A61P17/06 , A61P19/02 , A61P29/00 , A61P31/18 , A61P37/08 , A61P43/00 , C07D401/06 , C07D401/14 , C07D41/14
CPC分类号: C07D401/06 , C07D401/14
摘要: In its several embodiments, this invention discloses novel processes to prepare the compounds of formula II and formula IV:
摘要翻译: 在其几个实施方案中,本发明公开了制备式II和式IV化合物的新方法:
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2.Synthesis of quinoline 5-carboxamides useful for the preparation of PDE IV inhibitors 失效
标题翻译: 用于制备PDE IV抑制剂的喹啉5-甲酰胺的合成公开(公告)号:US07129357B2
公开(公告)日:2006-10-31
申请号:US10939740
申请日:2004-09-13
申请人: David R. Andrews , Suhan Tang , Wenxue Wu , Sami Y. Kalliney , Anantha Sudhakar , Christopher Nielsen
发明人: David R. Andrews , Suhan Tang , Wenxue Wu , Sami Y. Kalliney , Anantha Sudhakar , Christopher Nielsen
IPC分类号: C07D215/20 , C07D215/38
CPC分类号: C04B35/632 , C07C229/64 , C07D215/48 , C07D401/12
摘要: In one embodiment, the present application discloses a process for making the compound of the formula:
摘要翻译: 在一个实施方案中,本申请公开了制备下式的化合物的方法:
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3.Synthesis of quinoline 5-carboxamides useful for the preparation of PDE IV inhibitors 失效
标题翻译: 用于制备PDE IV抑制剂的喹啉5-甲酰胺的合成公开(公告)号:US20050124655A1
公开(公告)日:2005-06-09
申请号:US10939740
申请日:2004-09-13
申请人: David Andrews , Suhan Tang , Wenxue Wu , Sami Kalliney , Anantha Sudhakar , Christopher Nielsen
发明人: David Andrews , Suhan Tang , Wenxue Wu , Sami Kalliney , Anantha Sudhakar , Christopher Nielsen
IPC分类号: A61K31/47 , C07C229/64 , C07D215/14 , C07D215/48 , C07D401/12
CPC分类号: C04B35/632 , C07C229/64 , C07D215/48 , C07D401/12
摘要: In one embodiment, the present application discloses a process for making the compound of the formula:
摘要翻译: 在一个实施方案中,本申请公开了制备下式的化合物的方法:
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公开(公告)号:US09316082B2
公开(公告)日:2016-04-19
申请号:US13815156
申请日:2013-02-05
申请人: Christopher Nielsen
发明人: Christopher Nielsen
摘要: A cap assembly for sealing the open end of a well casing or other pipe includes a top plate for mounting on the open end of the pipe, a bottom plate spaced apart from the top plate, an upper expansible gasket sandwiched between the top plate and an upper clamping plate, a lower expansible gasket sandwiched between the bottom plate and a lower clamping plate, spacer sleeves extending between the clamping plates, bolts through the bottom plate, both gaskets and clamping plates, the sleeves and the top plate, and nuts on the bolts. When the bolts are tightened on the nuts, the gaskets expand to seal the pipe at spaced apart locations.
摘要翻译: 用于密封井套管或其他管道的开口端的盖组件包括用于安装在管的开口端上的顶板,与顶板间隔开的底板,夹在顶板和顶板之间的上可膨胀衬垫 上夹紧板,夹在底板和下夹板之间的下可膨胀垫片,在夹板之间延伸的间隔套筒,通过底板的螺栓,垫圈和夹紧板,套筒和顶板以及螺母 螺栓 当螺栓拧紧在螺母上时,垫片膨胀以在间隔开的位置密封管道。
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