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公开(公告)号:US20130012504A1
公开(公告)日:2013-01-10
申请号:US13619636
申请日:2012-09-14
申请人: William R. Baker , Shaopei Cai , Joshua Aaron Kaplan , Musong Kim , Jennifer Alissa Loyer-Drew , Stephane Perreault , Gary Phillips , Lafe J. Purvis, II , Marcin Stasiak , Kirk L. Stevens , Josh Van Veldhuizen
发明人: William R. Baker , Shaopei Cai , Joshua Aaron Kaplan , Musong Kim , Jennifer Alissa Loyer-Drew , Stephane Perreault , Gary Phillips , Lafe J. Purvis, II , Marcin Stasiak , Kirk L. Stevens , Josh Van Veldhuizen
IPC分类号: C07D215/54 , C07D401/14 , A61K31/496 , C07D413/12 , A61K31/538 , A61K31/4706 , C07D409/14 , A61P29/00 , A61P31/00 , A61P37/08 , A61P11/00 , A61P11/08 , A61P11/06 , A61P11/10 , A61P11/02 , A61K31/4709
CPC分类号: C07D215/54 , C07D401/12 , C07D409/14 , C07D413/12
摘要: Provided are compounds of Formula I: R1 and R2 together with the phenyl to which they are bound may form a bicyclic, fused heterocyclic ring, and all other variables are as defined herein, as well as their use in treating pulmonary inflammation or bronchoconstriction and compositions comprising and processes for preparing the same.
摘要翻译: 提供式I化合物:R 1和R 2与它们所连接的苯基一起可以形成双环稠合杂环,并且所有其它变量如本文所定义,以及它们在治疗肺部炎症或支气管收缩和组合物中的用途 包括及其制备方法。
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公开(公告)号:US20110275622A1
公开(公告)日:2011-11-10
申请号:US13103577
申请日:2011-05-09
申请人: William R. Baker , Shaopei Cai , Joshua Aaron Kaplan , Musong Kim , Jennifer Alissa Loyer-Drew , Stephane Perreault , Gary Phillips , Lafe J. Purvis, II , Marcin Stasiak , Kirk L. Stevens , Josh Van Veldhuizen
发明人: William R. Baker , Shaopei Cai , Joshua Aaron Kaplan , Musong Kim , Jennifer Alissa Loyer-Drew , Stephane Perreault , Gary Phillips , Lafe J. Purvis, II , Marcin Stasiak , Kirk L. Stevens , Josh Van Veldhuizen
IPC分类号: A61K31/4709 , C07D401/14 , C07D413/12 , A61K31/496 , A61K31/538 , A61P29/00 , A61K31/475 , A61P11/00 , A61P11/06 , A61P11/08 , A61P3/00 , C07D215/54 , A61K31/4706
CPC分类号: C07D215/54 , C07D401/12 , C07D409/14 , C07D413/12
摘要: Provided are compounds of Formula I: wherein X is: R1 and R2 together with the phenyl to which they are bound may form a bicyclic, fused heterocyclic ring, and all other variables are as defined herein, as well as their use in treating pulmonary inflammation or bronchoconstriction and compositions comprising and processes for preparing the same.
摘要翻译: 提供式I的化合物:其中X是:R 1和R 2与它们所连接的苯基一起可以形成双环稠合杂环,并且所有其它变量如本文所定义,以及它们在治疗肺部炎症中的用途 或支气管收缩剂及其组合物及其制备方法。
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公开(公告)号:US08394829B2
公开(公告)日:2013-03-12
申请号:US13103577
申请日:2011-05-09
申请人: William R. Baker , Shaopei Cai , Joshua Aaron Kaplan , Musong Kim , Jennifer Alissa Loyer-Drew , Stephane Perreault , Gary Phillips , Lafe J. Purvis, II , Marcin Stasiak , Kirk K. Stevens , Josh Van Veldhuizen
发明人: William R. Baker , Shaopei Cai , Joshua Aaron Kaplan , Musong Kim , Jennifer Alissa Loyer-Drew , Stephane Perreault , Gary Phillips , Lafe J. Purvis, II , Marcin Stasiak , Kirk K. Stevens , Josh Van Veldhuizen
IPC分类号: C07D215/38 , A61K31/04
CPC分类号: C07D215/54 , C07D401/12 , C07D409/14 , C07D413/12
摘要: Provided are compounds of Formula I: wherein X is: R1 and R2 together with the phenyl to which they are bound may form a bicyclic, fused heterocyclic ring, and all other variables are as defined herein, as well as their use in treating pulmonary inflammation or bronchoconstriction and compositions comprising and processes for preparing the same.
摘要翻译: 提供式I的化合物:其中X是:R 1和R 2与它们所连接的苯基一起可以形成双环稠合杂环,并且所有其它变量如本文所定义,以及它们在治疗肺部炎症中的用途 或支气管收缩剂及其组合物及其制备方法。
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