公开(公告)号：US20170112824A1

公开(公告)日：2017-04-27

申请号：US15332292

申请日：2016-10-24

Applicant: Wright State University

Inventor： Yong-Jie Xu ,  Amanpreet Singh

IPC: A61K31/4745 ,  A61K31/17 ,  A61K31/4174 ,  A61K31/4196 ,  A61K31/496 ,  A61K45/06 ,  A61K31/137

CPC classification number: A61K31/4745 ,  A61K31/137 ,  A61K31/17 ,  A61K31/4174 ,  A61K31/4196 ,  A61K31/496 ,  A61K45/06 ,  A61K2300/00

Abstract: Methods and pharmaceutical compositions for treating fungal infections in a patient via administration of hydroxyurea and an ergosterol synthesis inhibitor, hydroxyurea and a heme synthesis inhibitor, an ergosterol synthesis inhibitor and a heme synthesis inhibitor, or hydroxyurea, an ergosterol synthesis inhibitor, and a heme synthesis inhibitor.