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1.发明申请公开(公告)号：US20220127637A1
公开(公告)日：2022-04-28
申请号：US17572262
申请日：2022-01-10
发明人： Zheng Zhang , Xiaolu Li , Yuchen Zhang , Yarong Li , Huifang Dong , Jill Cai , Weichang Zhou , Chris Chen , Lili Mu , Chuanlong Tang
摘要： Provided is a polynucleotide the polynucleotide can be used as a WXRE transcriptional regulatory element used to increase the protein expression level of a protein expression system. A protein expression vector or a protein expression systems comprising the above-mentioned WXRE transcriptional regulatory element as well as the use thereof are also provided. The use of the WXRE transcriptional regulatory element can increase the expression level of a heterologous protein greatly with its biological activity unchanged.
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2.发明申请公开(公告)号：US20210254100A1
公开(公告)日：2021-08-19
申请号：US17268360
申请日：2019-08-14
发明人： Zheng Zhang , Xiaolu Li , Yuchen Zhang , Yarong Li , Huifang Dong , Jill Cai , Weichang Zhou , Chris Chen , Lili Mu , Chuanlong Tang
摘要： Provided is a polynucleotide, the polynucleotide can be used as a WXRE transcriptional regulatory element used to increase the protein expression level of a protein expression system. A protein expression vector or a protein expression system comprising the above-mentioned WXRE transcriptional regulatory element as well as the use thereof are also provided. The use of the WXRE transcriptional regulatory element can increase the expression level of a heterologous protein greatly with its biological activity unchanged.
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